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Jack Wadden Profile picture
Jack Wadden
@jackwadden
Post-doc @UMich in the @KoschmannLab. Research: intro-operative/rapid sequencing, high-accuracy cf-tDNA sensing. @nanopore hacker. He/him 🏳️‍🌈
May 18, 2021 • 25 tweets • 7 min read
Super excited to finally share this pre-print of our work demonstrating <30 minute sequencing-based somatic variant calls using @nanopore sequencers!

We had a need for speed. A (long) thread... 1/ Why focus on speed? Intraoperative sequencing. Being able to quickly (<1hr) identify actionable mutations *during surgery* has a host of amazing potential use-cases. Imagine generating a personalized molecular diagnostic during biopsy… 2/