Paresh Jadav, MD, FASN Profile picture
Roller-coasting along nephrons for a homeostatic milieu; asst professor-UT @McGovernMed; @UWnephrology ; @columbiakidney-transplant; #NSMC ; tweets r my own
Shanil Keshwani Profile picture 1 subscribed
May 12, 2021 21 tweets 8 min read
💥Tweetorial on C3 Glomerulopathy (C3G)
⚡️what is C3 Glomerulopathy?
⚡️how to establish the diagnosis?
⚡️what is the role of Complements? 💥C3 Glomerulopathy (C3G) represents rare kidney diseases affecting both children & adults
⚡️It encompasses 2 distinct conditions:
1- DDD (dense deposition disease)
2- C3GN (C3 Glomerulonephritis)
Aug 1, 2020 16 tweets 6 min read
Tweetorial on 'Antigens in Primary Membranous Nephropathy & Epitope Spreading' ..inspired by excellent clinicians @GlassockJ & @NephRodby whose daily case discussions on @ASNCommunities have been like a virtual fellowship @RenalFellowNtwk @NSMCInternship @kidney_boy
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💥Primary MN
⚡️one of the commonest causes of nephrotic syndrome
⚡️reflects histological change of GBM thickening with little or no proliferation or infiltration
⚡️many antigens identified recently, starting with PLA2R
⚡️15 to 20% of MN remain negative for any known antigens
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Jul 23, 2020 18 tweets 7 min read
My attempt on "Decoding the HLA" with tweetorial & some slides/VisualArts @kidney_boy @NSMCInternship @Nephro_Sparks @hswapnil @rheault_m @RenalFellowNtwk @ssfarouk #Transplant
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💥MHC complex
⚡️cluster of genes--> encodes HLA molecules
⚡️located on chromosome 6p21
⚡️over 200 genes; of which 40% involved in immune response
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Jul 17, 2020 16 tweets 5 min read
My maiden attempt at Tweetorial-- 💥on STARRT-AKI trial. @NephJC @kidney_boy @Nephro_Sparks @ssfarouk @STARRTAKI @hswapnil
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💥Background:
⚡️AKI is associated with high risk of death in ICU
⚡️Initiation of dialysis early has conceivable advantages
⚡️Appropriate timing for dialysis is uncertain
⚡️Previous studies👇 have shown discrepant results