Jakob Macke Profile picture
#ML & #AI for scientific discovery · Prof @uni_tue @ml4science @mackelab @BernsteinNeuro · Adjunct @mpi_is · Fellow @EllisForEurope · currently hiring postdocs
Nov 12, 2019 15 tweets 8 min read
New: "Training deep neural density estimators to identify mechanistic models of neural dynamics” biorxiv.org/content/10.110… @ppjgoncalves @janmatthis @deismic_ Nonnenmacher @kaandocal Bassetto @chc1987 @Bill_P_ @SaraAnnHaddad @TPVogels @dvdgbg. Our biggest project so far! Thread: Models in neuro are ideally built on our assumptions about underlying mechanisms, often using classical theories (Hodgkin Huxley, E/I Balance, ..).
Catch is: Getting models and data to agree can be tricky, and people spend time tuning parameters by hand or with heuristics. (2/n)