Infectious diseases, family, friends, science and arts. ESCMID Past President but here only my own opinions
May 3, 2020 • 9 tweets • 1 min read
I still don't know if remdesivir works but I know all around this drug is weird. Let's see (thread)
It is active in vitro. It does not mean much. It was also against Ebola but did not show relevant effect in vivo.
Feb 6, 2020 • 11 tweets • 2 min read
Había pensado no escribir nada sobre el nuevo coronavirus para no contribuir involuntariamente a esta locura. Pero la cosa está llegando a un punto que me obliga a hacerlo. A ver si lo consigo… (hilo)
Los datos: (a) Los epidemiólogos estiman que el índice de reproducibilidad estaría entre 2 y 3 (cada caso lo transmite, de media, a otras 2-3 personas).
Sep 16, 2018 • 12 tweets • 4 min read
My comments on MERINO (thread) (1/12) on @JAMA_current 1st, CONGRATS @padstamundo@davidantibiotic and coauth - a big achievement. Disclosures: I've published papers in favor of BLBLI as alternative to carbapenems; I am @davidantibiotic friend. I was member of the DSMB of MERINO
2/12. Primary outcome was 30-day mortality. Problem: ALL deaths were unrelated to the infection but due to underlying condition, mostly metastatic/terminal cancer (Table e6). Differences in secondary endopoints were not significant (but on the side of favouring meropenem)
