As we wander through our daily lives, our brain process billions of terabytes of information, much of which is highly ambiguous. Ever wonder how our brains resolve this uncertainty? For example, imagine you see something super strange, like those weird rabbit-duck hybrid illusions. Even though the same visual input is hitting your retina, you can process that information differently to see either the duck or the rabbit.

The PDF of our recent paper in @Brain1878 with @DrYohanJohn @NeuroYogacara @C__OCallaghan @jaaanaru @ishan_walpola @GabWainstein and @NatashaL_Taylor on making sense of the serotonergic system just dropped (but you'll have to wait til the end of this thread to get the PDF...) The paper stemmed from a talk I gave to @DrYohanJohn's discussion group about how amazing the neuromodulatory system is: . Given my past work, I mainly just spoke excitedly about how interesting the noradrenergic system is...

New paper out today in @TrendsCognSci with @GabWainstein @NatashaL_Taylor @DrBMunn @eli_j_muller. Strap yourselves in for a twitter thread about one of our favourite parts of the brain: the noradrenergic locus coeruleus and its impact on the rest of the brain... (1/16) In my lab, we think a lot about how different parts of the brain work together -- we're especially interesting in how the widespread projections of the ascending arousal system can influence ongoing activity in target regions, such as the thalamus, cortex and cerebellum (2/16)

New review paper out today in @NatureNeuro with @DrBreaky, @eli_j_muller, @DrBMunn, @rosalynjmoran and @Joana_Cabral__, based on a symposium that we hosted at @OHBM in 2019 on the importance of the neuromodulatory arousal system for shaping whole brain dynamics (1/n) Prior to the symposium, @DrBreaky @eli_j_muller and I had a great chat (fighting through jet-lag and brutal head colds) where Michael laid out a framework for linking neuromodulatory tone to population-level neural dynamics using insights from computational modelling (2/n)

Everywhere you look in systems neuroscience, you see evidence for low-dimensional manifolds -- but how do these distributed patterns of neural activity relate to neurobiology? In a recent pre-print, @DrBMunn @eli_j_muller @GabWainstein and I tested the hypothesis that different arms of the ascending arousal system should differentially change attractor landscape dynamics -- i.e., the way that the low-dimensional brain state changes over time.

Ever wondered how different systems in the brain work together to coordinate attention, cognition and awareness? If so, this is the thread for you... Many of our best models for how the mammalian brain works are focussed on the cerebral cortex. When you look at a human brain, it's really hard to miss on the outer surface of the brain, and there's also ++ evidence from clinical neurology that lesions lead to specific symptoms

Very excited to announce the publication of our new paper in @NatureNeuro: rdcu.be/bhO9H with @russpoldrack, @DrBreaky, @spornslab, @kaylena88, @p_t_brain, Sanmi Koyejo and Rick Shine! The work was inspired by a skype conversation with @spornslab – we were both interested in finding ways to track the dynamic trajectory of the whole network of the human brain over time, but didn’t love the standard idea of chopping up time series into discrete windows.