Author of Principia Qualia, Symmetry Theory of Valence, Neural Annealing, Principles of Vasocomputation. Friend to the future.
Jan 2, 2025 • 5 tweets • 2 min read
Niacin is notorious for its flush reaction; opening blood vessels
Niacin (nicotinic acid) injections stop LSD trips within minutes
Pretty suggestive evidence for vasocomputation, and that psychedeics’ characteristic effects arise from their impact on the vascular system specifically
Last year I proposed “vasocomputation,” that vascular tension acts as a special type of memory that regulates neural dynamic range. Recently at @joinedgecity I shared some updates: how ‘thoughts’ are patterns of vascular tension, and implications for Buddhist enlightenment
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We were taught in school the vascular system is “plumbing for blood” — tubes that transport nutrients & waste. Vasocomputation suggests this misses 90% of what this system does — the vascular system adaptively shifts tension to help neurons compute
As far as I can tell, the LLM game is about data quality much moreso than anything else. We see that over and over in papers: all LLM architectures converge on the same answer (approximation of the data). But garbage in, garbage out — the data itself is centrally important
Jan 29, 2024 • 13 tweets • 4 min read
In the beginning there was sensation
Humans developed the ability to freeze sensations, then used these frozen pieces to construct a grammar for thought (vasocomputation)
This led to words, magical spells that can conjure sensations in both caster and target
If a dolphin wants to explain there’s a school of fish nearby, it will send the sound of a sonar return from a phantom school of fish — literally the *sensation* of fish. I suspect this is a good model for early human language — “magic spells that involuntarily invoke sensations”
Sep 27, 2023 • 22 tweets • 7 min read
Nattokinase saved my life a few years ago. You should probably consider taking it.
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NK is a cheap, powerful, and easy to get fibrinolytic that dissolves blood clots and plaques. Imo it’s also the supplement with the best +EV for longevity and cognitive health. (1/n)
The body produces clots (fibrin tangles) to prevent blood loss and mop up small debris like pathogens. Blood loss was a big danger throughout most of our evolutionary past so this system tends to be at high readiness, with clots constantly forming and dissolving. Your background rate of clot formation can be inferred by a blood test for D-dimer, a marker for dissolved clots. en.wikipedia.org/wiki/D-dimer
