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Jonas Bovijn Profile picture
Jonas Bovijn
@jonasbovijn
Physician-scientist in drug discovery @RegeneronDNA | Prev: DPhil @bdi_oxford, @rhodes_trust scholar | genomics/drug dev/health/biotech/🇿🇦
Aug 23, 2022 • 12 tweets • 12 min read
🚨 Publication alert: largest to date multiancestry exome analysis of body fat distribution discovers INHBE mutations associated with favorable adiposity and PROTECTION from diabetes! 🚨

Out today in @NatureComms

👇🧵 key takeaways below…

nature.com/articles/s4146… Image Fat distribution: MAJOR BUT OVERLOOKED risk factor for diabetes & heart attacks globally

Storing⬆️fat in waist and⬇️in hips gives ⬆️⬆️⬆️risk – independent of overall body fat (👇)

🚨Lots of drug development in obesity; almost none for fat distribution

nature.com/articles/s4146… Image