1/ Treating hepatocellular carcinoma (HCC) with macrovascular invasion (MVI) has always been challenging. New research compares two approaches—surgery and stereotactic body radiotherapy (SBRT)—providing fresh perspectives on how we care for these patients.

Let’s dive in. 🧵


2/ This study used propensity score matching to ensure fair comparisons between the two groups. The primary outcome was overall survival (OS), with secondary outcomes including local control and distant recurrence rates.

Here’s what they found: 🧑‍⚕️👇

Is there a role for Local Tx of the Primary Tumor for Patients with Metastatic Cancer?

🚫Many studies demonstrate no benefit.
📌We performed a MetaAnalysis to evaluate the average effect of Local Tx across various tumors.

A thread🧵#AMSM #PRIMETX
redjournal.org/article/S0360-…

1/25 Critics of Local Tx to the Primary Tumor

📌 Many providers think local control of the primary tumor in the setting of M1 dz is akin to “closing the barn door after the horse has bolted”
📌 Ian Tannock wrote a fantastic article on this back in 2000.

pubmed.ncbi.nlm.nih.gov/11759650/

2/