Josh Schiffman Profile picture
Postdoc @ New York Genome Center & Weill Cornell
Jan 4, 2023 15 tweets 6 min read
I'm excited to share a paper w co-1st @ar_davino, @TamaraPrietoF + @landau_lab. We introduce tools to study the heritability + plasticity of cell state diversity in somatic evolution, now possible w single-cell tech. It all began with a simple question... biorxiv.org/content/10.110… #scRNAseq has revealed that across biology, tissues contain lots of cellular diversity, with different groups of cells expressing different sets of genes. But how are these cells ancestrally related? Are cells that look similar also closely related? What would this mean?