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Ninaad Lasrado, PhD Profile picture
Ninaad Lasrado, PhD
@lasradoN
Postdoc @BarouchLab/ @harvardmed/@BIDMChealth | Ph.D @unlincoln | Interested in mRNA therapeutics and vaccine development against infectious diseases
Sep 5, 2023 • 11 tweets • 3 min read
New data from our lab @BarouchLab on the Neutralization Escape of BA.2.86, FL.1.5.1, EG.5.1, and XBC.1.6. We had a well-defined cohort of 66 participants, with people who did and did not receive bivalent mRNA vaccines. A thread🧵. This was a massive effort from the @BarouchLab members, especially from @airisyc @jesslmiller17 @mrowe1625 @trisha_anand31 @CamilleRMazurek @BIDMC_CVVRTrial and the ever wonderful @bettekorber1!
Jan 23, 2023 • 6 tweets • 6 min read
Our new preprint on the durability of #bivalent #mRNA vaccines against #XBB.1.5 is out now! We looked at both humoral & cellular immune responses up to 3 months post boost! @BarouchLab @airisyc @ocpowers5599 @mrowe1625

TL;DR: PLEASE GET A BOOSTER!

biorxiv.org/content/10.110… We first looked at the nAbs induced by bivalent mRNA vaccines against BQ.1.1, XBB.1, and XBB.1.5 at baseline, 3-weeks-post boost and 3 months post boost. nAb levels peaked at week 3 post-boost, but waned over a period of time. Neutralizing antibody titers of bivalent mRNA vaccines again