Lukas Simon Profile picture
Molecular data science
Jun 21, 2021 4 tweets 4 min read
Happy to announce that our (@zhao7900, @YinyingWang) #deeplearning method INSCT for integration of #scrnaseq is out @NatMachIntell go.nature.com/2Uq73If! We extended triplet neural nets by defining 'batch-aware' triplet sampling, which overcomes batch effects in #scrnaseq data. Instead of sampling triplets the traditional way, we added constraint to sample anchor-positives from different & anchor-negatives from the same batch. (We expect this approach to be also useful outside of #scrnaseq data - happy to discuss w anyone interested).