Share this page!

Enter URL or ID to Unroll

You can paste full URL like: https://x.com/threadreaderapp/status/1644127596119195649
or just the ID like: 1644127596119195649

How to get URL link on X (Twitter) App

  1. On the Twitter thread, click on or icon on the bottom
  2. Click again on or Share Via icon
  3. Click on Copy Link to Tweet
  4. Paste it above and click "Unroll Thread"!
  5. More info at Twitter Help
Maddie Lee Profile picture
Maddie Lee
@m_janelee
@stanfordimmuno PhD Candidate | Minnesota girl | @wustl grad ‘19 | studying NK cells in COVID with the @blish_lab | she/her
3 subscribers
Dec 27, 2022 • 10 tweets • 5 min read
Our paper on SARS-CoV-2 evasion of NK cell killing is officially out in @CellReports! tldr; SARS-CoV-2 suppresses danger signals that are supposed to help NK cells recognize and kill infected cells so the virus can spread instead of being stopped by the immune system. A 🧵(1/10) NK cells are supposed to kill virally-infected cells to stop the virus from spreading. Unfortunately, they’re terrible at killing SARS-CoV-2-infected targets compared to uninfected “bystander” cells! 2/10
Jun 22, 2022 • 11 tweets • 5 min read
We have a new preprint out today on biorxiv examining the ability of NK cells to kill SARS-CoV-2-infected cells! tldr; they’re pretty terrible at it.
biorxiv.org/content/10.110…

A tweetorial: (1/11) To gauge how well healthy NK could specifically kill SARS-CoV-2-infected cells, we infected A549-ACE2s with enough virus to get 50% of cells infected after 48 hours. Then, we performed flow-based killing assays using purified, healthy NK cells. (2/11)