My lab’s 5-year NIH R01 grant, awarded to study gene therapy for hearing loss, was abruptly terminated. I want to share how this action has been incredibly harmful and disruptive, not just to my lab, but to the scientific process itself. 1/15 A little over two years ago, I was ecstatic to receive my very first R01 grant from the NIDCD. Our research focuses on restoring hearing by targeting the underlying mechanisms of stereocilia elongation, a subject I've dedicated my career to since my PhD. 2/15

If you'd like to hear the whole story as to how we got from the movie on the left to the movie on the right, come join me for a "tweetorial" starting now!

https://twitter.com/RebeccaDRobbins/status/1169230127248506880

First - the problem: We love our point scanning imaging systems. They are versatile and can get amazing resolution. But if you want to max out your resolution, you better have a boatload of patience, and nearly invincible samples. Unfortunately, I rarely have either.

My very first senior author manuscript. Equally important: My very first preprint! So stoked to finally be a direct participant in this long overdue process for accelerating biology.

Actin chromobody imaging reveals sub-organellar actin dynamics biorxiv.org/content/10.110… Fair warning: If you don’t care about actin, organelles, or imaging, you may want to mute this thread. The rest of you kids should buckle up, cuz I’m gonna take you on a little journey. Will update this thread when I am able.