Excited to share our new #method, scDRS, for associating **individual cells** to disease by integrating #scRNA-seq + #GWAS, providing #polygenic disease risk enrichment beyond tissues or cell types.

biorxiv.org/content/10.110… scDRS assesses excess expression of a set of putative disease genes constructed from GWAS, using an appropriately matched empirical null distribution to compute p-values. (2/n)