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Mitchell (Min Woo) Kim Profile picture
Mitchell (Min Woo) Kim
@mitchkim_mw
MD/PhD at WashU | neuroimmune-ing in the @kipnislab | UCLA 16’
Oct 30, 2024 • 7 tweets • 2 min read
Transforming traditional views laid by “CNS immune privilege,” our research uncovers the brain’s purposeful presentation of self – that is the brain engages with the immune system through “guardian” peptides to ensure immune tolerance. @jonykipnis
nature.com/articles/s4158… Utilizing immunopeptidomics, we identified CNS-derived “guardian” peptides bound to MHC II molecules with an unexpected representation of MBP. Image