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Qasim Khan, MBBS, MS, FRCPC Profile picture
Qasim Khan, MBBS, MS, FRCPC
@mqkMD
Transplant Hepatologist @westernuGI| MASH, MetALD, PTMS | @MayoClinicGIHep @Columbia Alum|@humasaeedulhaq's Husband|Girl Dad👨‍👩‍👧‍👧 | Musician🎸🎤| 🇨🇦🇵🇰
Jun 4, 2020 • 8 tweets • 6 min read
@AmCollegeGastro Virtual Grand Rounds meets #livertwitter - NASH - 🔑 Pts:
🩺 NAFLD Dx ➡️5% steatosis ; NASH has specific path criteria (🎈 dilatation, M-D bodies, etc); Exclude🍻 and other etiologies; Assoc w/ met. RFs
🌎 Prevalence 25%👨; 7-10%👧🧒 ; In DM II ➡️ 55.5%; 🍃 History - NAFLD➡️NASH➡️Cirrhosis➡️HCC. Non-linear progression also exists! HCC w/o cirrhosis (0.592%/year);
📈Predictors of Progress: (a) Met. RFs; (b) Stage of Fibrosis (>= F2)
⚕️ #2 indication for LT and ⬆️; #1 in ♀️
⬆️DALYs (07-17)
📊By 2030 ~800,000 excess liver deaths;