So my lady friend eats a quite varied diet. Mostly whole foods, but some processed. Lots of veggies, some fruit, a little red meat, often fish, eggs, cheese, poultry, yogurt. She has bacon for breakfast two or so days a week, and I'm talking 4-6 rashers. 1/n She has bread nearly every meal, enjoys pasta, rice, quinoa, beans, potatoes, nuts, seeds, and occasionally ice cream, fudgsicles, and milk (yuck) chocolate. She has juice for breakfast (no more than 8oz). 2/n

I am fully aware of the discussion on lowering LDL-C, and avoiding statins, PCSK9i, and all cholesterol-lowering drugs. I'm also aware that sky-high LDL-C on a carnivore or VLCD can be mitigated by adding a few high-quality whole food carbs into the diet. No need to rehash that in this thread.

Here's my n=1 results from adding more carbs into my diet, and taking only 10mg ezetimibe daily. Please recall I suffered a stress-related stroke in late January, have intracranial arterial stenosis, and am having trouble controlling my BP, which I also

Ten years ago this week, I quit heavily drinking alcohol cold turkey and quit eating carbs. I weighed 256lb (I'm ~5'11'"), waist:hip was 1.16, and waist:height was 0.7, trigs were 393. I had gout, depression, hypertension, anxiety, asthma, zero energy, metabolic syndrome, 1/n and couldn't walk from my garage to my shed and back. I was on 7 prescription drugs and several OTC. I was miserable and was planning on not making it to age 56. After decades of ADA/AHA/DGA-approved low-fat, five-a-day, healthy whole grain, limit saturated fat, eat the 2/n

Looking … Looking …

@iPolicy @bigfatsurprise Read. Learn.

forbes.com/sites/nancyhue… @iPolicy @bigfatsurprise npr.org/sections/thesa…

Many times over the decades (since 1974), I've been right where I am today: At a low, nearly optimal weight after a fairly profound weight loss. Before 2014, I reduced weight via calorie restriction and willpower. It's a miserable process rife with hunger and (unknown to me at the time, negative metabolic and physical changes). After 2014, when I went lower carb, I could still restrict calories, but with a higher protein, higher fat, lower carb diet, there was much less hunger. But my weight still yo-yoed because when I wasn't consciously

Nutrition for Precision Health, powered by the All of Us Research Program

"The goal of the NIH Common Fund’s Nutrition for Precision Health, powered by the All of Us Research Program, is to develop algorithms that predict individual responses to food and dietary patterns."
1/3 The objectives of the study are:

1. To examine individual differences observed in response to different diets by studying the interactions between diet, genes, proteins, microbiome, metabolism and other individual contextual factors
2/3

Cardio:

Looks at lab report — LDL-C 270 (350 last time), LDL-P 2504 (3421) — and recites should be <100 and <1000. Says nothing about HDL 77 or TRIG 69 or LP-IR <25). Freaks out. I can tell this report colors everything else he says, and how he says it. 1/n "Your CAC was abnormal." (17 this time, zero three years ago). Then adds, but anything less 100 is lower risk. "Your carotids are worse this time." Then adds but the % occlusions are not very accurate. Recommends a statin, plant-based diet, avoiding SFA, yada yada. 2/n

The good news: USDA 2020 Dietary Guidelines for Americans (DGA) apply to all healthy adults

The bad news (especially to those who have followed previously-published guidelines, some for decades): Only 12% of adults are healthy

What are 7 of 8 Americans supposed to do? Fewer than 7% of adults have good cardiometabolic health, according to Tufts.

"five components of health: levels of blood pressure, blood sugar, blood cholesterol, adiposity (overweight and obesity), and presence or absence of cardiovascular disease (heart attack, stroke, etc.)"

This is the 3rd day of 3 high-fat, calorie-doubled days before a lipid panel tomorrow. Curious to see if TC/LDL is lower than the last time, when I was eating my normal LCHF diet. CAC is late next week, and cardio f/u the week after that. I'm going to ask for a selfpay CCTA then. Still waiting on @Labcorp to post results from a early morning Tuesday last (4/11) blood draw. Results are usually available by now.🧐 The suspense is maddening!

Question about the 3:1 or 2:1 keto diet for tumor suppression

Adequate protein vs excess energy

115 lb IBW (52kg), 122 lb current weight, maintaining on 1400 kCal/day 1.6 g/kg protein target is 84 g/day protein, which means 168 g/day fat at 2:1 ratio
which is 1848 kCal/day

So adequate protein with 2:1 F:P results in excess energy.

@USDANutrition National Strategic Partners … include large, national organizations such as healthcare corporations, media outlets, grocery retailers, health professional associations, restaurant chains, and food manufacturers.

This is who tells us what we should eat: They all share one thing in common.

Today is the consult with the neurosurgeon. If you have a minute to send good vibes, please do. I haven't been this anxious ever.

https://twitter.com/mrc314/status/1621121252495597568

Verdict: 7+ hour brain surgery -> ICU -> 4+ days in hospital. Pathology will determine exact type and necessity of chemo/radiation. Lots to go wrong, but we can't just leave the thing alone. Thanks everyone for the good vibes and kind words. It really helps.

What I'm doing right this minute and why. It will likely change!

1) Set your protein 1.4-1.6g/kg/d, more if you exercise lots
2) Set your carbs ≤20 if you're sick, ≤60 if you're fat-adapted and metabolically well, maybe more if you exercise lots 1/4 3) The rest fat: tallow, lard, butter; coconut, avocado, olive oil (if from trusted sources)

Eat eggs, cheese, full fat dairy, beef (ruminant); pork & chicken can be high in n6; berries, 100% chocolate; avocado, toasted coconut if you like

NO: refined carbs, sugar, PUFA 2/4

You won't die if you stop eating carbs. You won't die if you fast for 18 hours. You won't die if you make changes to you diet to find out what works for you. If you feel like you're going to die, change what you're doing. 1/4 Because when you eat wrong for a long time, you actually might die from that. And you probably won't feel it since you're likely focused on going for your next sugar high, finding that bliss mirage. The best thing you can do is really appreciate your body's signals. 2/4

An "ordinary" large egg contains 5g of fat, 1.5g saturated.

nutritiondata.self.com/facts/dairy-an… Eggland says their eggs contain 25% less SATURATED fat than ordinary eggs.

They trumpet this right on the label:

Age 55: Before I started a LC/keto diet, my cardiologist said nothing about the TRIGS and low LDL-C, other than lose 10 pounds. 1/5 Age 59: After I was on a LC/keto diet for a while, my lipidologist looked at my bloodwork and said, "You have familial hypercholesterolemia!" Judging by my TC numbers over time, it looks like I can alter my🧬at will then.🙄 2/5

I get such a kick out of my cardiologist. On my first visit, he saw my lab report and just knew I shouldn't be buying green bananas, my cholesterol was so high, and I don't eat fruits and veg. He remembered I eat keto or Paleo (same thing to him I think). After 1/4 things had settled down, he confirmed we found high HDL, low trigs, low CRP, low insulin and A1c, and a zero CAC, and that he didn't see the need for a statin. Plus, this visit I lost several pounds since I was there 16 months ago. You can see the wheels 2/4

Two choices: Follow the recommendations of your doctors, RDs/CDEs, and other HCPs. Eat low-fat, favor seed oils over animal fats, eat 7x a day, lots of heart-healthy whole grains, high fiber, limit meat, no full-fat dairy, etc. You know the drill. Take a 1/10 statin for your LDL-C, BP meds if you're over 120/80, allopurinol for your gout, steroid creams for your fungal infections, inhalers for your asthma, antihistamines for your allergies, metformin and SGLT2i and insulin for your blood sugars, and more pills 2/10

We are screwed: THREAD

https://twitter.com/mrc314/status/1549146367532179456

Ann Arbor (Michigan) Summer Art Fair

An institution since 1960.

The shape and size of the people have changed over the years. Can you spot the difference? 1/ 1967 & 1969