This builds on our previous study journals.plos.org/plosmedicine/a… which includes a description of the derivation of the genetic instruments and their relationships with risk of CHD employing multivariable Mendelian randomization
Apr 5, 2019 • 9 tweets • 3 min read
What if I said that we had a multitude of observational studies, each showing a potential protective effect of alcohol at moderate doses on risk of heart disease and stroke. And that despite our best efforts, elucidating causality was nigh-impossible owing to (i) feasibility,
(ii) funding, (iii) ethics, etc. And that despite some strong efforts, randomized controlled trials had been abandoned due to perceived bias by industry nih.gov/news-events/ne…
