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Professor M Z Khalil Profile picture
Professor M Z Khalil
@mzkhalil
Professor of Medicine / Cardiology ⛔ Learning is a talent Teaching is a gift
Jun 7, 2019 • 5 tweets • 3 min read
A 68 y o male with type-2 DM, CAD, CCF (EF~35%), PAD, and history of gouty arthritis presented with dyspnea and LL edema.

Which of the following drugs is appropriate therapy for his edema?

A) Furosemide
B) Indapamide
C) Empagliflozin
D) Bumetanide
E) Metolazone

#cardiotwitter Correct answer is (C)

Hyperuricemia is a common adverse effect of loop or thiazide diuretics and may precipitate acute gouty arthritis.

Treating type-2 DM with an SGLT2 inhibitor promotes osmotic diuresis, natriuresis, and reduces uric acid by increasing its excretion.