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Philippe Batut Profile picture
Philippe Batut
@philippe_batut
Long-range gene regulation in development: enhancers, genome organization & noncoding RNAs | Postdoc Levine lab @Princeton | PhD Gingeras lab @CSHL
Feb 4, 2022 • 6 tweets • 5 min read
Thrilled to share our latest work, now in @ScienceMagazine! Exploring how #3DGenome organization controls #transcription dynamics during #development. A few highlights below! #InHoxWeTrust
@XinyangBing
Zachary Sisco
@J_Raimundo_
@Michal_Levo
Mike Levine
science.org/doi/10.1126/sc… The Drosophila genome is organized by 2 types of elements: tethers mediate focal contacts, while insulators establish #TAD boundaries. We used genome editing and live transcription imaging to explore their roles in the temporal regulation of #Hox gene expression in the embryo. Image