Our research is out in ⁦@bmj_latest⁩ today: “Comparative risk of thrombosis with thrombocytopenia syndrome or thromboembolic events associated with different covid-19 vaccines: international network cohort study from 5 Eur countries and the US” bmj.com/content/379/bm… This is to our knowledge the 1st international study of #covidvaccine compartive safety. We studied the risk of thrombosis and/or thrombocytopenia in the 28d after adenovirus- vs mRNA-based vax in DE, ES, FR, NL, UK, and the US

New paper out today @JTHjournal : "Genetic risk and incident venous thromboembolism in middle-aged and older adults following #COVID19 vaccination" . A short 🧵 1/n) Some #COVIDvaccines have been associated with increased risk of blood clots (VTE). We wanted to understand if genetic predisposition to VTE would predict risk of post-vaccine VTE, and if vaccination interacted with underlying genetics

New paper published in ⁦@bmj_latest⁩ : “Association between covid-19 vaccination, SARS-CoV-2 infection, and risk of immune mediated neurological events: population based cohort and self-controlled case series analysis”. A 🧵 bmj.com/content/376/bm… 1) previous reports and research have suggested an association between some #CovidVaccines and immune neurological conditions including facial paralysis and Guillain-Barré syndrome. We had access to unique data to study this, and to research if #COVID19 itself can cause these

Tres estudios sobre la severidad de #omicron ayer, en un solo dia 🧐. Un resumen despues de leerlos con detalle 🧵TL;DR: es demasiado pronto, necesitamos mas datos con seguimiento mas largo 1/n - 3 estudios con caracteristicas distintas. el de SA tiene mayor N, pero es dificil extrapolar x diferencias socio-demograficas notables y un sistema sanitario muy diferente. Los d Inglaterra y Escocia son mas utiles para ES. Los 3 traen buenas noticias y matices

Our study “Comparative effectiveness of the BNT162b2 vs ChAdOx1 vaccine against Covid-19” is available and awaiting feedback at ⁦@medrxivpreprint⁩ . A short 🧵 medrxiv.org/content/10.110… 1/3- We analysed 235,181 UK Biobank participants aged 50 years or older and vaccinated with one or two doses of BNT162b2 or ChAdOx1. Follow up run until 18/10/2021. IPW weighting was used to minimise confounding, & negative control outcomes to rule out residual bias

WE ARE RECRUITING 🥳🥳
We look for 2 senior or post-doctoral statisticians or data scientists to join my team at @UniofOxford Short 🧵to tell you why you should apply.

The detail is here: my.corehr.com/pls/uoxrecruit… 1) If you come & work with us you will access awesome large data to research #COVID19 #COVIDVaccines and many methodological aspects of pharmacoepidemiology and the use of 'real world data'

Nuevo articulo publicado en @bmj_latest : "Associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with covid-19 in nursing homes and healthcare workers in Catalonia: prospective cohort study" . Hilo en castellano para el publico general 🧵 1/6) Las personas que viven en residencias sufrieron gran mortalidad y ingresos durante la primera ola de #COVID19, dada su susceptibilidad y patologia previa. En este estudio miramos el efecto de #VacunaCOVID19 en este grupo, que estaba infra-representado en ensayos clinicos

Nou article al @bmj_latest "Associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with covid-19 in nursing homes and healthcare workers in Catalonia: prospective cohort study" . Fil en catala pel public no cientific 🧵 1) Les persones que viuen en residencies van patir gran mortalitat i ingressos durant la primera onada, donada la seva susceptibilitat i patologia previa. En aquest estudi vam estudiar l'efecte de #VacunaCOVID19 en aquest grup, que no s'havia inclos gaire en estudis previs

New paper in @bmj_latest !! "Associations of BNT162b2 vaccination with SARS-CoV-2 infection and hospital admission and death with covid-19 in nursing homes and healthcare workers in Catalonia: prospective cohort study" #COVID19Vaccines Plain English 🧵 bmj.com/content/374/bm… 1/6) We used routine health data from primary care and hospital records linked to lab tests and mortality data, and studied 28,456 nursing home residents, 26,170 nursing home staff, and 61,791 healthcare workers

Oigo aun a mucha gente "minimizando" el impacto de esta quinta ola porque solo afecta a jovenes, y estos no se ponen enfermos. Ojo que hay mucho que perder si no se hacen las cosas bien! 🧵 1.Los datos de Reino Unido dicen que aunque la vacunacion (que por cierto aqui hay mejor cobertura que en Spain) reducira ingresos, no los parara. El numero de ingresos esta semana en UK es >50% superior a la previa, y vamos por >500 ingresos diarios

Una reflexión sobre el concepto de “overshooting”. O por qué se equivoca UK liberando todas las restricciones cuando el país se acerca a la inmunidad de rebaño 🧵 El concepto de inmunidad de rebaño se vende como un umbral mágico en el que la pandemia se desvanecerá. Pero esto, por supuesto no es así. Lo que ocurrirá es que la R bajará (y se mantendrá) <1, y la pandemia remitirá progresivamente

100 years since women were admitted as full members @UniofOxford . What a waste all the previous years without them! Meet 100 amazing women with whom I'm lucky to work @OxfordMedSci medsci.ox.ac.uk/100-women-of-o… . A thread on a few I know more closely (alphabetical order)🧵 Alice @HarinAlice is an awesome senior research nurse now deployed to emergency public health research. We share many values including our EU origins and love for languages, beverages and culture beyond our borders. More here: medsci.ox.ac.uk/100-women-of-o…