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Priya Rao, MD Profile picture
Priya Rao, MD
@priyaraomd
Mom, physician, urologic pathologist & Professor of Pathology @MDAndersonNews. ⚾️ and 🏊🏻‍♀️mom. Opinionated, but opinions my own. #PathTwitter
Sep 3, 2020 • 5 tweets • 4 min read
#GUPath twitter brain trust. Posting for a colleague.

37yo man with a renal mass.

Pos for PAX8, keratin. Neg for NE markers, GATA, WT1 and everything else.

We are stumped. Thoughts? Anyone seen something like this before? We thought of adult Wilms’s but IHC doesn’t support. ImageImageImageImage @Williamson_SR @Kiril_T_Can @johncheville @rovingatuscap @MichelleDunno17 @FionaMacPath @daniel_berney #GUPath
May 15, 2020 • 4 tweets • 3 min read
Renal bx from a woman in her late 50s, with a renal mass and metastasis. This biopsy is from the kidney. This was a highly infiltrative, high grade tumor with a desmoplastic background. Continued 👇 #GUpath ImageImage The referring institute reported + PAX8, CK7, - GATA3, CK20, TTF1. O/S diagnosis was collecting duct carcinoma.

Upon review by us, we realized that the pt was AA and ordered an INI-1 which was negative.

Diagnosis: Renal medullary carcinoma (confirmed by Hb electophoresis) 👇
May 14, 2020 • 4 tweets • 3 min read
Continuing yesterdays theme. Renal bx from a mass in a 55 yo. This one showed more stroma and the nuclei lining the cysts were less "ugly". Continued 👇#GUpath ImageImageImage Mass was resected and was <4 cm and well circumscribed. 👇 ImageImageImage
May 12, 2020 • 4 tweets • 3 min read
Incidental renal mass. Stains and diagnosis 👇#GUpath ImageImageImage PAX8 (highlighting epithelium) and HMB45 (stains stromal component). ImageImage
May 3, 2020 • 4 tweets • 2 min read
Renal tumor in a 19 year old. Stains and diagnosis 👇 #GUpath ImageImageImage CD117 and Synaptophysin (pictures) +. PAX8 - Image
Apr 30, 2020 • 5 tweets • 2 min read
I had a colleague from private practice ask me if I ever make a diagnosis of RCC with leiomyomatous stroma (RCCLMS). I thought this would be a good time to share an example. Continued 👇 ImageImage An excellent summary of the molecular findings was published this mth in AJSP by @rajalbshah & @Kiril_T_Can suggests that these are unique tumors that harbor mutations in the TSC, MTOR and ELOC (TCEB) genes and are distinct CCRCC. Diffuse expression of CK7 is key.