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Jakub Schimmelpfennig Profile picture
Jakub Schimmelpfennig
@psychedmt
First steps as #psychedelics (DMT) and #consciousness researcher. Chief of Psychedelic and Consciousness Research Group on @SWPSUniversity Neuropsychology 🧠 🍄
Mar 7 • 27 tweets • 6 min read
🧵 Endogenous DMT: What Do We Really Know?
Two recent papers shed new light on endogenous DMT, its biosynthesis, regulation, and function:
📄 Exploring DMT: Endogenous Role and Therapeutic Potential – by @psychedmt
📄 N,N-Dimethyltryptamine (DMT) in Rodent Brain: Concentrations, Distribution, and Recent Pharmacological Data – by Steven Barker
This thread summarizes key findings.

These studies challenge the idea that DMT exists in only trace amounts and has no biological role.

Let’s dive in. ⬇️🧵Image 1/25 DMT: More Than a Psychedelic?
DMT is an endogenous compound present in plants, animals, and humans. Recent findings show brain levels comparable to classic neurotransmitters, challenging the idea that DMT is only a trace molecule.