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Sai Zhang Profile picture
Sai Zhang
@saizhang0
Assistant Professor @YaleBIDS @YaleMed | #AI × #Biomed | Views are my own.
Apr 16, 2025 • 10 tweets • 4 min read
📢New preprint alert! Myalgic encephalomyelitis/chronic fatigue syndrome (ME/CFS) is a complex disease that is affecting more people than we thought, yet it is significantly underrecognized and poorly studied. 1/n
medrxiv.org/content/10.110… We systematically examined the genetics of ME/CFS using AI and WGS. We generated the largest WGS dataset to date for ME/CFS, based on 3 cohorts including @mecfsbiobank. We then developed HEAL2, a deep learning framework that predicts ME/CFS risk from rare coding variants. 2/n Image