𝗣𝗔𝗥𝗞𝗜𝗡𝗦𝗢𝗡’𝗦 & 𝗟𝗜𝗚𝗛𝗧 – 𝗔𝗡 𝗨𝗡𝗧𝗢𝗟𝗗 𝗦𝗧𝗢𝗥𝗬

A mega thread on how sunlight, circadian rhythms, and red light therapy protect the brain and improve Parkinson’s symptoms.

I have linked over 50 studies.

🧵
I wrote this thread because I have a client who has seen massive benefits from sunlight and photobiomodulation for helping manage his Parkinson's disease symptoms.

*𝘿𝙞𝙨𝙘𝙡𝙖𝙞𝙢𝙚𝙧: 𝙉𝙤𝙣𝙚 𝙤𝙛 𝙩𝙝𝙞𝙨 𝙞𝙨 𝙢𝙚𝙙𝙞𝙘𝙖𝙡 𝙖𝙙𝙫𝙞𝙘𝙚*

𝗦𝘂𝗻𝗹𝗶𝗴𝗵𝘁 & 𝗜𝗺𝗺𝘂𝗻𝗲 𝗦𝘆𝘀𝘁𝗲𝗺 𝗥𝗲𝗴𝘂𝗹𝗮𝘁𝗶𝗼𝗻

If you are struggling with autoimmune disease this will interest you.

Vitamin D is the tip of the iceberg. The body is making another powerful immune modulator every time you step outside.

THREAD 🧵 Quick Disclaimer: None of this is medical advice and is meant for educational purposes only.

🧵𝗟𝗲𝗽𝘁𝗶𝗻 𝗦𝗲𝗻𝘀𝗶𝘁𝗶𝘃𝗶𝘁𝘆 & 𝗠𝗲𝗹𝗮𝘁𝗼𝗻𝗶𝗻 𝗔𝗿𝗲 𝗜𝗻𝘁𝗲𝗿𝘁𝘄𝗶𝗻𝗻𝗲𝗱

Let's dive into why & how your light environment & a deficiency in melatonin can lead to leptin resistance = obesity, nuked metabolism, hypothyroidism, T2DM & chronic hunger.

🔖Bookmark this (it's a long one)
Melatonin production does not only prepare the body for restorative sleep, but it helps regulate energy homeostasis through food intake, energy storage & energy expenditure.

Everyone on long-term medications should be doing this.

𝗜𝘁 𝗰𝗼𝘂𝗹𝗱 𝘀𝗮𝘃𝗲 𝘆𝗼𝘂𝗿 𝗵𝗲𝗮𝗹𝘁𝗵 𝗮𝗻𝗱 𝗿𝗲𝗱𝘂𝗰𝗲 𝗿𝗶𝘀𝗸 𝗼𝗳 𝘀𝗶𝗱𝗲-𝗲𝗳𝗳𝗲𝗰𝘁𝘀. 🧵 Many medications deplete key nutrients over time.

This can lead to side effects that seem unrelated - fatigue, brain fog, muscle cramps, weakened immunity, etc.

The list is literally endless.

🧵 𝗟𝗼𝘄 𝘀𝘁𝗼𝗺𝗮𝗰𝗵 𝗮𝗰𝗶𝗱 𝗿𝗲𝗱 𝗳𝗹𝗮𝗴𝘀 𝗼𝗻 𝗮 𝗚𝗜 𝘁𝗲𝘀𝘁 (𝗚𝗜-𝗠𝗔𝗣, 𝗚𝗜𝗙𝗫, 𝗚𝗜𝟯𝟲𝟬)

Stomach acid is crucial for proper digestion and absorption of nutrients as well as maintaining microbial balance. Overview:
1) H pylori infection
2) Low elastase
3) High bacillus, staph, strep
4) Food poisoning - E. Coli

2 Bonuses at the end.

🧵𝗡𝗮𝘁𝘁𝗼𝗸𝗶𝗻𝗮𝘀𝗲: 𝗘𝘃𝗲𝗿𝘆𝘁𝗵𝗶𝗻𝗴 𝘁𝗵𝗲𝗿𝗲 𝗶𝘀 𝘁𝗼 𝗸𝗻𝗼𝘄

𝗧𝗵𝗲 #𝟭 𝗲𝗻𝘇𝘆𝗺𝗲 𝗳𝗼𝗿 𝗼𝗽𝘁𝗶𝗺𝗶𝘀𝗶𝗻𝗴 𝗰𝗮𝗿𝗱𝗶𝗼𝘃𝗮𝘀𝗰𝘂𝗹𝗮𝗿 𝗵𝗲𝗮𝗹𝘁𝗵.

Nattokinase breaks blood clots, reverses atherosclerosis, lowers blood pressure, and optimizes lipid profiles. Disclaimer: None of this is medical advice and this is for educational purposes only.

𝗗𝗘𝗘𝗣 𝗗𝗜𝗩𝗘 𝗢𝗡 𝗧𝗛𝗜𝗔𝗠𝗜𝗡𝗘 𝗙𝗢𝗥 𝗠𝗜𝗧𝗢𝗖𝗛𝗢𝗡𝗗𝗥𝗜𝗔𝗟 𝗛𝗘𝗔𝗟𝗧𝗛

Vitamin B1, also known as thiamine, plays crucial roles in many metabolic processes and cellular functions.

🧵Let's dig in.... Thiamine acts as a cofactor for important enzymes, including:

- Cytosolic transketolase
- Pyruvate dehydrogenase (PDH)

Both of these are essential for effective energy metabolism. And energy metabolism is king.

Do you need to take omega-3 supplements if you eat adequate amounts of seafood?

There is plenty of research emphasizing the importance of omega-3s PUFAs such as EPA & DHA, but are natural sources enough?

Let's take a look... 🧵
Typically supplements will provide 1-2g of omega-3s...

But how much can we get from whole foods?

Taurine & Mitochondrial Function

In in-depth🧵exploring how taurine improves mitochondrial health, and why it matters for metabolic disease, diabetes and heart disease. Taurine is a semi-essential amino acid that can be synthesized from methionine and cysteine using vitamin B2,3 & 6 as cofactors.

Testosterone & Leptin

Leptin is one of the master hormones that actively regulate myriad other hormones including the thyroid, adrenal, pancreatic and sex hormones.

THREAD 🧵 Leptin controls energy metabolism within the body on a macro scale. As with most things in biology, it is not good or bad, the story lies in restoring coherence, and re-establishing leptin sensitivity.

Grounding & Blood Clots

A 🧵 on why zeta-potential maxxing matters if you want to avoid blood clots. Zeta potential is the electrostatic difference between the surface of a solid particle and the liquid within which it is immersed.

Nutrition for Mitochondrial Function Omega Thread:

This 🧵will shine a light on why I prioritise micronutrient density.

Mitochondrial function relies on optimal nutrient levels as they play pivotal roles in driving energy metabolism and ATP production.

(Bookmark this)

THREAD

Several vitamins and minerals are crucial for mitochondrial function serving as cofactors in energy metabolism or exerting antioxidant effects.

High Protein To Lose Weight:

Everyone always says that a high protein diet is beneficial for weight-loss, but never tell you why...

This 🧵will explore all of the mechanisms behind protein's weight-loss benefits. The WHO recommends that protein should constitute 10-15% of energy intake... but this may not be enough.

A high protein diet is considered to contain 20-30% of energy intake from protein.

1 gram of protein per pound of body weight is a great benchmark.

Taurine & Mitochondrial Function

In in-depth🧵exploring how taurine improves mitochondrial health, and why it matters for metabolic disease, diabetes and heart disease. Taurine is a semi-essential amino acid that can be synthesized from methionine and cysteine using vitamin B2,3 & 6 as cofactors.

A Guide on Near-Infrared Light

This 🧵covers the details of our natural light environment and the optics that the human body has evolved to take advantage of it.

Light is life... let me show you how. The sun represents the single largest energy input to the human body with a solar spectrum extends between 250-4000nm.

Chronobiology & Sleep Patterns:

This 🧵explores the science of chronotypes and how our artificially lit modern world is nuking our sleep and circadian health.

If you stare at a screen at night, sleep late and wake up tired, this will apply to you. Structure of the Thread:

1) Intro to Chronotypes
2) Modern Environmental Mismatch
3) Re-Syncing with a Natural Environment
4) How to Advance your Circadian Phase

The Mitochondrial Origin for Type 2 Diabetes Mellitus

This 🧵will explore the thesis that insulin resistance and subsequent T2DM is caused by mitochondrial dysfunction.

In a previous thread I described Douglas C. Wallace's "Mitochondrial Paradigm for Chronic Disease".

Now it is time to tell a story of how exactly this manifests in T2DM.

x.com/sam_soete/stat…

Vitamin K Omega Thread:

Want to know why everyone combines vitamin D supplementation with vitamin K?

This 🧵goes deep into the mechanisms of action of vitamin K, and its synergistic relationship with vitamin D in preventing vascular calcification and maintaining BMD. This thread will cover:

• Types & sources of vitamin K
• Causes of vitamin K deficiency
• Vitamin K & bone health
• Vitamin K & vascular calcification/CVD
• Interaction b/w vitamin K & D

Mitochondria lie at the heart of chronic, neolithic disease.

This 🧵explores the mitochondrial paradigm of degenerative disease pioneered by Doug Wallace.

This shit is interesting... And the implications are unimaginable. Chronic disease is not a genetic story.

Genetic mutations cannot explain the meteoric rise of chronic disease in recent decades. The problem lies not in our genes, but in our environment.

Vitamin B12 Deficiency 🧵

Micronutrients > Macros & Calories

But what is the point if your body can't effectively absorb or retain these nutrients?

Let's take a look why you may have a vitamin B12 deficiency. Let's get the easy wins out of the way first.

1) Vegetarian or vegan diets

Leptin Sensitivity & Melatonin Are Intertwinned:

This is an unbelievably important connection to understand.

Let's dive into why & how a deficiency in melatonin production can lead to leptin resistance = obesity, nuked metabolism & chronic hunger. Melatonin production does not only prepare the body for restorative sleep, but it helps regulate energy homeostasis through food intake, energy storage & energy expenditure.