Work in progress | Evolution | Ecology | Systems Biology | Experiments | Theory | Running a lab @ucsdbiosciences
May 21, 2023 • 8 tweets • 2 min read
My postdoc @JosephMatheson2 and I were sending off my former undergraduate student Minkyu Kim to graduate school at @USC and giving him some advice over a beer. I thought it might be useful to share.
1. Grad school is a marathon, not a sprint. Focus on finishing rather than on running fast.
Sep 19, 2021 • 26 tweets • 4 min read
I’ve been thinking recently about the generality of scientific results. Lack of generality is a common and often lazy critique of papers and grants. But how do we actually know whether a result is or would be general? And what is “general” anyway? 1/26
Here are some simple observations that helped me think a bit more clearly about this topic. The first most basic observation is that generality pertains only to mental constructs (theories or models), not data. Data are data. The interpretation of data can be general or not. 2/26
Jul 13, 2020 • 19 tweets • 5 min read
@GrantKinsler, @KSamerotte, @PetrovADmitri, I read your paper over the weekend. So much to think about. I certainly haven't fully digested it, but it’s amazing work!
Some thoughts/questions below.
We started thinking along similar lines in our paper by @erjerison et al. nature.com/articles/s4155…
Your “fitness profiles” are our “pleiotropic profiles”. We also did dim. reduction and saw mutants form clusters. But you pushed this approach so much further. Really cool!
