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https://twitter.com/sudokuvariante/status/1805373729989370156That is basically consistent with data:
https://x.com/sudokuvariante/status/1787902102485848251
https://x.com/sudokuvariante/status/1740410801406824884
https://twitter.com/sudokuvariante/status/1799073046466310626➖Let's look at how many patients this "large RCT" managed to recrute for this arm: 153 !
https://twitter.com/sudokuvariante/status/1792232982134010117This narrative has been pushed by young scientists claiming they checked raw data of clinical trials:
https://twitter.com/eh_den/status/1787528626000347451What we knew from NEJM publication was ~4 months follow-up 74% efficacy based on 0.4% incidence of covid-19 in vaccine group vs 1.5% in placebo group.
https://twitter.com/sudokuvariante/status/1764040548967420200I already shared the criteria for futility of the trial, based on Version 5.0 of Adaptive Design Report , which specify the HR=1.2 threshold for the clinically meaningful effect:
https://twitter.com/sudokuvariante/status/1764040559600042324
https://twitter.com/sudokuvariante/status/1761762266112729593These 2 important results should be referenced and discussed when you model mass administration of the drug and make the assumption it reduces the spread of the virus. None of them is referenced here.
https://twitter.com/Acermendax/status/1755179845959426406
https://twitter.com/sudokuvariante/status/1740288226085175669Preliminary: let @samiahurst explain what pseudoscience is