Discover and read the best of Twitter Threads about #panoramic
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This is a really important paper. Some have said it's a bad news story...
The question is should £1bn have been spent on this drug in 2021 following just a prelim analysis of a much smaller trial...
However, before we start, bravo @ChrisColButler & team👏
papers.ssrn.com/sol3/papers.cf…
The question is should £1bn have been spent on this drug in 2021 following just a prelim analysis of a much smaller trial...
However, before we start, bravo @ChrisColButler & team👏
papers.ssrn.com/sol3/papers.cf…
First, a little on molnupiravir (Lagevrio).
This is a nucleoside drug, or "nuc", originally named EIDD-2801 by scientists at Emory University. It was named Molnupiravir after Thor's hammer, Mjölnir.
Nucs are the building blocks of genetic material, so RNA or DNA. Nucs are a well
This is a nucleoside drug, or "nuc", originally named EIDD-2801 by scientists at Emory University. It was named Molnupiravir after Thor's hammer, Mjölnir.
Nucs are the building blocks of genetic material, so RNA or DNA. Nucs are a well
established class of agents used against RNA viruses as they target a unique feature of these viruses - the RNA dependent RNA polymerase, an enzyme that makes more RNA using RNA as a template. We don't have these in mammalian cells, so the idea is you can target this selectively
Day 3 of #Omicron symptoms was my worst so far, with fatigue & a very heavy head, alongside sneezing. My tight chest, feeling of reduced lung capacity and tickly lung sensation had subsided slightly, as did the coughing, that had become painful on Day 2 #Oximeter down to 96%...
...so I slept a lot on Day 3.
But now it's 1am on Day 4 and I feel full of life. Fatigue gone. No more headache. Slight wheeze still, Oximeter 96%; no appetite, but sense of smell and taste are fine.
Wonder whether the worst is over, as I'm double AZ-jabbed plus Pfizer-boosted?
But now it's 1am on Day 4 and I feel full of life. Fatigue gone. No more headache. Slight wheeze still, Oximeter 96%; no appetite, but sense of smell and taste are fine.
Wonder whether the worst is over, as I'm double AZ-jabbed plus Pfizer-boosted?
I can't find evidence of people relapsing into worsening symptoms post-Day 3, but my lungs are my weakness... Am I good right now because I slept so much over the last 3 days?
Tomorrow I begin my participation in the @UniofOxford #Molnupiravir (antiviral) trial.
Link follows...
Tomorrow I begin my participation in the @UniofOxford #Molnupiravir (antiviral) trial.
Link follows...
