#OncoAlert #AACR20 More mature data emerging from China. This review by Dr. Zhang at Tongji in Wuhan discusses patients with cancer and #COVID19. Interesting to contrast these with data from US, Italy, Spain, France, etc - some trends just reflect patient populations served.
#OncoAlert #AACR20 In the Liang report from @TheLancetOncol, we saw 1% of #COVID19 patients had cancer. In this Wuhan report from 3 hospitals (1/13/20-2/26/20), it was 2.2% (25% lung, 14% esophageal, 11% breast), 30% stage IV. 60/40 split male/female. 71% community acquired.
#OncoAlert #AACR20 In 28 patients with cancer and #COVID19, 36% required mechanical ventilation, 29% mortality with 21% still hospitalized. For those discharged, median hospitalization 18.4 days. For those with severe events, median 7 days from COVID diagnosis to event.
#OncoAlert #AACR20 Serial scans show #COVID19 related lung changes. Note the fibrosis emerging at day 25. Will long-term sequela impact respiratory function, quality of life? Will this vary by prior lung pathology, prior radiation, prior pneumonitis, etc?
#OncoAlert #AACR20 Analyses to identify risk factors for severe events such as recent anti-cancer therapy (14d), radiographic findings. IO therapy not a clear risk. Numbers though are small and this is where large ongoing registries (such as #TERAVOLT) will help with perspective.
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