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Jun 13, 2020, 10 tweets

#WorldBloodDonorDay2020: Century-old Convalescent Plasma Therapy Ignites New Hopes for #COVID19 Treatment

weather.com/en-IN/india/ne…

#WorldBloodDonorDay #coronavirus

(📸: Mahesh G/BCCL Vijayawada)

Experts continue to stress that the therapy holds promise, and there is a growing need for plasma donors across the country to give a fighting chance for #COVID19 patients with severe symptoms.

➡️What is convalescent plasma therapy?⬅️

It is a passive antibody therapy where the immunity of a recovered patient is transferred to a sick person using blood plasma. When attacked by a pathogen, our immune system produces proteins called antibodies to fight the infection.

If the infected person can produce sufficient antibodies, he can recover from the disease caused by that pathogen.

➡️Has the therapy been used before?⬅️

-Passive Antibody Therapy is an age-old technique to treat infectious diseases.
-German physiologist Emil von Behring and Japanese physician Baron Kitasato Shibasaburo are the pioneers of modern therapeutic Immunology.

➡️Is the therapy effective?⬅️

-First #COVID19 patient who underwent #PlasmaTherapy in India recovered during last week of April in Delhi. Positive results have come from states like Gujarat, Kerala.

-The first patients to receive it in Maharashtra failed to recover & died.

-Several studies in multiple countries have reiterated the importance of ‘passive antibody therapy’ as a success to treat #COVID19.

-Some researchers have expressed reservations against using the therapy, quoting some side effects like transfusion-transmitted infections.

➡️Is plasma therapy safe?⬅️

↪️Like any other medical procedure, there are substantial risks involved in convalescent plasma therapy as well.

↪️During the process of blood transfusion, there are chances of inadvertent infections getting transferred to blood cells of the patient.

↪️The treatment can suppress the body’s natural immune system, thereby leading to chances of re-infection, though such cases have not been reported yet.

↪️There are set criteria for a patient to be eligible for plasma therapy.

Though plasma therapy offers new light in the complex treatment of #COVID19 infections, availability of infrastructure, medical facilities, suitable donors, medicines and equipment pose a wide hindrance.

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