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Original info & analysis only, RT=archive, avoiding future repeating past. Mirror mirror on the wall, who's the first person release SC2 🧬(s) to the world?

Mar 7, 2021, 16 tweets

#SARSCOV2 #origin This thread is about analysis of origin search of SARS-COV-2 in various outbreaks in China. The 'origin search' is more for epi purpose, not quite similar as the 'origin research' in viral evolution. Of course, first cases and Huanan market include here.
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#SARSCOV2 #origin First, let's have some taste of the mutation analysis of full genome sequencing with some covid-19 patients in Wuhan, by #IVDC
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#SARSCOV2 #origin Then, the set up of task force to assess the food safety risk of potential transmission via cold chain.
3/n

#SARSCOV2 #origin
Initial results of the first batch of samples from Wuhan on 2nd January 2020. After Visionmedicals & BGI got their preliminary results ID as SARSr-CoV. 4/n

#SARSCOV2 #origin
Initial results of the 2nd batch of samples from Wuhan on 2nd January 2020. Received GMT+8 23:00, MiSeq. 5/n

#SARSCOV2 #origin seven specimens from severe pneumonia patients in Beijing hospital used as control. 6/n

#SARSCOV2 #origin
Just break in for Huanan market a bit. We all knew an environmental origin searching working plan against Huanan seafood market was drafted on 1st Jan, 2020. And leading person of this environmental sampling, Jun Liu, also is the deputy of George Gaofu's lab.

#SARSCOV2 #origin
a bit background story by China CDC own declaration, pay attention
a) full sequence obtained on 3rd Jan.
b) testing protocol established on 4th Jan.
c) shared genome and image via GISAID on 12th Jan.
d) a bit description of Jun Liu. 6/n

chinacdc.cn/yw_9324/202003…

#SARSCOV2 #origin
These results of environmental sampling and analysis can also found in publications.7/n

#SARSCOV2 #origin
Analysis of initial samples .8/n

#SARSCOV2 #origin
Analysis of initial samples .9/n

#SARSCOV2 #origin
Analysis of initial samples. 10/n

#SARSCOV2 #origin
Analysis of initial samples. 11/n

#SARSCOV2 #origin
Various outbreaks in China & COLD CHAIN. 12/n

#SARSCOV2 #origin
Various outbreaks in China & COLD CHAIN. 13/n

#SARSCOV2 #origin
Various outbreaks in China & COLD CHAIN. 14/n

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