Prismatic Publication: Sherlock Holmes of computational biology studies is revealed in @biorxivpreprint bit.ly/3wScuhn @jbloom_lab in story that combines Wuhan #SARSCoV2 @NIH deleted sequences telltale emails, @googlecloud HT @baym 1/
Dr. Bloom recovered #SARSCoV2 sequences that are closer to bats that any early 2020 human viral samples despite the order to destroy all early viral samples /2
Dr. Bloom applied equally insightful institutional sleuthing and sequence matching and evolutionary analysis to find sequences missing from the Short Read Archive @NIH but then resurrected their digital ghosts from @googlecloud /3
despite requests (without explanation) for the deletion of those sequences from the Short Read Archive /4
These sequences are then placed in context relative to the other sequences previously published /5
Which leads Dr. Bloom to wonder about the missed scientific and public health opportunity and why the sequences were deleted /6
This paper will be used in classes for years to demonstrate the full toolkit of sequence and evolutionary computational biology and the agency of biologically sophisticated data scientists. Students read this paper!
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