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Royal College of Psychiatrists Profile picture
Royal College of Psychiatrists
@rcpsych
Royal College of Psychiatrists: Improving the lives of people affected by mental illness. Please DM for enquiries.

Jun 23, 2021, 18 tweets

We are delighted to be joined by Sophia Frangou - @Frangougroup Argyris Stringaris - @argStringaris and Heather Whalley who will be discussing: Dimensional and Categorical Psychopathology in Youth: Cognitive and Brain

#RCPsychIC

Presenter Profiles:

Sophia Frangou - @Frangougroup
Argyris Stringaris - @argStringaris
Heather Whalley - @heatherwhalley2

#RCPsychIC

Taking this approach

#RCPsychIC

Two studies will be discussed - ABC study and Imagen both have significant overlap at least conceptually

Imagen study we had 2000 young people

#RCPsychIC

The results of this study the effect is more pronounced in different regions

Imagen study:

#RCPsychIC

ABCD Study

-Diffused profile of brain organisation and the environment
-Negative effect on adverse perinatal brain activity

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ABCD study

Psychological outcome – suicidality nearly 700 children had considered ending their life – looking at what exposures in the study associated with suicidality.

#RCPsychIC

Parting thoughts from Sophia Frangou - @Frangougroup

#RCPsychIC

Welcoming to talk now is Argyris Stringaris - @argStringaris

#RCPsychIC

Basic challenges to psychiatric research in depression

-Genes
-Environment
-Active gene-environment correlation
-Passive gene-environment correlation
-Gene-environment interactions

#RCPsychIC

Reward aberrations in humans

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Longitudinal findings and specificity for depression

#RCPsychIC

Depression definitions

There were 9197 depression types

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Defining reward

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Welcome Dr Heather C Whalley! who is speaking about the trajectory of brain structural development in young people at familial risk of mood disorder

#RCPsychIC

Important: all individuals were well at the beginning and over time some became unwell

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There are structural brain differences at baseline

#RCPsychIC

Thank you to our speakers today Sophia Frangou - @Frangougroup Argyris Stringaris - @argStringaris and Dr Heather Whalley.

We hope you found the talk informative and educational as much as we did!

#RCPsychIC

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