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Royal College of Psychiatrists Profile picture
@rcpsych
Jun 23, 2021 • 18 tweets • 11 min read • Read on X
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We are delighted to be joined by Sophia Frangou - @Frangougroup Argyris Stringaris - @argStringaris and Heather Whalley who will be discussing: Dimensional and Categorical Psychopathology in Youth: Cognitive and Brain

#RCPsychIC Image
Presenter Profiles:

Sophia Frangou - @Frangougroup
Argyris Stringaris - @argStringaris
Heather Whalley - @heatherwhalley2

#RCPsychIC Image
Taking this approach

#RCPsychIC Image
Two studies will be discussed - ABC study and Imagen both have significant overlap at least conceptually

Imagen study we had 2000 young people

#RCPsychIC Image
The results of this study the effect is more pronounced in different regions

Imagen study:

#RCPsychIC Image
ABCD Study

-Diffused profile of brain organisation and the environment
-Negative effect on adverse perinatal brain activity

#RCPsychIC Image
ABCD study

Psychological outcome – suicidality nearly 700 children had considered ending their life – looking at what exposures in the study associated with suicidality.

#RCPsychIC
Parting thoughts from Sophia Frangou - @Frangougroup

#RCPsychIC Image
Welcoming to talk now is Argyris Stringaris - @argStringaris

#RCPsychIC Image
Basic challenges to psychiatric research in depression

-Genes
-Environment
-Active gene-environment correlation
-Passive gene-environment correlation
-Gene-environment interactions

#RCPsychIC Image
Reward aberrations in humans

#RCPsychIC ImageImage
Longitudinal findings and specificity for depression

#RCPsychIC ImageImage
Depression definitions

There were 9197 depression types

#RCPsychIC Image
Defining reward

#RCPsychIC Image
Welcome Dr Heather C Whalley! who is speaking about the trajectory of brain structural development in young people at familial risk of mood disorder

#RCPsychIC Image
Important: all individuals were well at the beginning and over time some became unwell

#RCPsychIC Image
There are structural brain differences at baseline

#RCPsychIC Image
Thank you to our speakers today Sophia Frangou - @Frangougroup Argyris Stringaris - @argStringaris and Dr Heather Whalley.

We hope you found the talk informative and educational as much as we did!

#RCPsychIC

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More from @rcpsych

Royal College of Psychiatrists Profile picture
Jul 13, 2023
Next up at #RCPsychIC is session S40 on ‘The placebo effect: insights for translational research and clinical practice’.

This will be chaired by Professor Samuele Cortese (@CorteseSamuele).
The first speaker in this session is Dr Nathan Huneke (@NathanHuneke) who will be talking about ‘Current knowledge of the placebo effect in anxiety disorders and future directions’ Image
Nathan begins by highlighting 50 years of drug trials for anxiety disorders.

Very few have been successful because we don’t understand the neurobiology and there has been poor validity of pre-clinical trials.

But placebo response is also a factor.
Read 18 tweets
Royal College of Psychiatrists Profile picture
Jun 23, 2022
Session S39 at #RCPsychIC is on ‘Precision medicine and personalised healthcare in psychiatry’ and is chaired by @RachelUTG.

This topic is the subject of a (free-to-view) @TheBJPsych themed issue:

cambridge.org/core/journals/…
First up in this session is Dr Rajeev Krishnadas (@WalkKD) from University of Glasgo. He was a guest editor for the BJPsych Special Issue and is talking about five points to consider when reading a translational machine learning paper.

#RCPsychIC Image
Starts off with explaining what ‘machine learning’ is with a definition of:

“Set of approaches that estimate the best mathematical/statistical model that explain or predict the relationship between ‘variables’”

#RCPsychIC
Read 25 tweets
Royal College of Psychiatrists Profile picture
Jun 24, 2021
Join us now in the auditorium of Virtual Congress to see one of our last talks of the day: "How to work with homeless people" #RCPsychIC
The agenda on today's talk is "Making services work for homeless people" with Dr Philip Timms @philip_timms a Consultant psychiatrist at the National Psychosis Service #RCPsychIC
After that, we have "Trauma-focussed practice with homeless people" with Dr Peter Cockersell @petercockersell the Chief Executive at Community Housing and Therapy #RCPsychIC
Read 17 tweets
Royal College of Psychiatrists Profile picture
Jun 24, 2021
Our final session of #RCPsychC virtual Congress we are talking about Religious Delusions and Hallucinations: Significance, meaning, and narrative with Dr Alison J Gray @revdraligray, Professor Christopher C.H. Cook @cchcook and Dr Angela Woods @literarti
Book: Hearing voices, demonic and divine

#RCPsychIC
Respondents: hearing voices

#RCPsychIC
Read 16 tweets
Royal College of Psychiatrists Profile picture
Jun 24, 2021
In one of our final split session talks of #RCPsychIC 2021, we'll be hearing from @RachelUTG, @PsychMarwaha and @sameerjauhar, chaired by Professor Allan Young: Care of Adult Mental Ill-Health: Getting it right from the start.
@RachelUTG @PsychMarwaha @sameerjauhar The first talk comes from @RachelUTG. Interesting findings regarding clozapine in treating first episode psychosis. #RCPsychIC
@RachelUTG @PsychMarwaha @sameerjauhar "Can we use anti-depression medication in a more thoughtful way?" asks @RachelUTG at #RCPsychIC
Read 10 tweets
Royal College of Psychiatrists Profile picture
Jun 24, 2021
So -we're nearly at the end of our first virtual #RCPsychIC - but there's one more set of split sessions to go! On this thread you can follow the 57th split session of this amazing event, which is about Dual Diagnosis from the public, clinical + academic perspective.
Our first speaker is Caroline Turiff, who has been diagnosed with a range of conditions inc OCD and PTSD, and is an award winning investigative broadcast journalist. #RCPsychIC
I've read 70% of people with drug dependency who have a dual diagnosis so it is the norm for them, she says. #RCPsychIC
Read 22 tweets

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