John Damianos, M.D. Profile picture
@MayoClinicGIHep Gastroenterology & Hepatology Fellow. Yale Internal Medicine, Dartmouth Med. Microbiome, probiotics, brain-gut, diet, motility, IBD, MedEd 🇬🇷

Oct 23, 2021, 22 tweets

Kicking off #ACG2021 with the #esophagus! @RenaYadlapati on "taming the tube!"

@AmCollegeGastro #VaxxedNMasked

Candida esophagitis. Some pill and liquid retention.

Obstructive symptoms without mechanical cause ▶️ HRM (+/- TBE/FLIP)

Need to test supine AND upright

❓Is LES relaxation adequate? ▶️ IRP

If > 15, not relaxing adequately, concern for #achalasia-like process

100% failed peristalsis
IRP 10.5 (upper limit of normal)

Absent contractility? Type I achalasia?

Type I: classic
Type II: often precursor to TI. Panesophageal pressurization

Treatment: LES-directed therapy– POEM, LHM, pneumatic dilation

Type III spastic achalasia

Treatment: stop opioids; tailored POEM

Inconclusive #achalasia? Time to reach for other tools (TBE, FLIP).

🐦

Elevated IRP but evidence of intact peristalsis? Could be EGJOO 🧇

Some 🧇 is artifact, other is true #motility disorder (#achalasia-like)

Need symptoms PLUS findings

Disorders of peristalsis

HCE can be a response to #GERD

Both HCE and DES are only relevant if there are associated symptoms. May be response to #GERD or opioid use.

LES relaxes normally, normal IRL, 100% failed peristalsis

Can be seen in connective tissue disorders or #GERD

Ineffective esophageal motility

💎s from @RenaYadlapati on "taming the tube"

"Don't look at your patient in a vaccum. Look for symptoms and other findings."

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