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May 6, 2022, 11 tweets

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John Aucott, MD
Persistent symptoms in Lyme disease
Associate Professor of Medicine @HopkinsMedicine @JohnsHopkinsSPH @jhrheumatology
#LymeDiseaseAwarenessMonth

John Aucott, MD
Persistent symptoms in Lyme disease are often difficult to measure and lead to delayed diagnosis and poorer outcomes.
#LymeDiseaseAwarenessMonth

John Aucott, MD
The SLICE study seeks to measure the Persistent symptoms in Lyme disease
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John Aucott, MD
The SLICE has shown that persistent symptoms of Lyme disease is a REAL measurable condition.
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John Aucott, MD
The SLICE study seeks to measure the Persistent symptoms in Lyme disease. Is clearly evident in 13.7% of this group.
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John Aucott, MD
The number of patient with long term Lyme disease is in the hundreds of thousands. With Long COVID the numbers will be in the millions.
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John Aucott, MD
Definition of persistent Lyme disease.
Note: Standard serology is NOT helpful!
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John Aucott, MD
Three hypotheses for causes of Persistent symptoms in Lyme disease, includes persistent infection, immune dysregulation/inflammation, neural network alterations.
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John Aucott, MD
The SLICE study ongoing research show there are REAL physiological reasons for cognitive changes. Including reduced brain blood flow, glia inflammation, altered neural networks.
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John Aucott, MD
The most important component when examining a patient with Lyme disease is to listen to your patient.
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John Aucott, MD
Off table treatments for persistent Lyme disease. Ongoing clinical trials network will hopefully provide more answers.
#LymeDiseaseAwarenessMonth

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