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May 6, 2022 11 tweets 9 min read Read on X
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John Aucott, MD
Persistent symptoms in Lyme disease
Associate Professor of Medicine @HopkinsMedicine @JohnsHopkinsSPH @jhrheumatology
#LymeDiseaseAwarenessMonth
John Aucott, MD
Persistent symptoms in Lyme disease are often difficult to measure and lead to delayed diagnosis and poorer outcomes.
#LymeDiseaseAwarenessMonth
John Aucott, MD
The SLICE study seeks to measure the Persistent symptoms in Lyme disease
#LymeDiseaseAwarenessMonth
John Aucott, MD
The SLICE has shown that persistent symptoms of Lyme disease is a REAL measurable condition.
#LymeDiseaseAwarenessMonth
John Aucott, MD
The SLICE study seeks to measure the Persistent symptoms in Lyme disease. Is clearly evident in 13.7% of this group.
#LymeDiseaseAwarenessMonth
John Aucott, MD
The number of patient with long term Lyme disease is in the hundreds of thousands. With Long COVID the numbers will be in the millions.
#LymeDiseaseAwarenessMonth
John Aucott, MD
Definition of persistent Lyme disease.
Note: Standard serology is NOT helpful!
#LymeDiseaseAwarenessMonth
John Aucott, MD
Three hypotheses for causes of Persistent symptoms in Lyme disease, includes persistent infection, immune dysregulation/inflammation, neural network alterations.
#LymeDiseaseAwarenessMonth
John Aucott, MD
The SLICE study ongoing research show there are REAL physiological reasons for cognitive changes. Including reduced brain blood flow, glia inflammation, altered neural networks.
#LymeDiseaseAwarenessMonth
John Aucott, MD
The most important component when examining a patient with Lyme disease is to listen to your patient.
#LymeDiseaseAwarenessMonth
John Aucott, MD
Off table treatments for persistent Lyme disease. Ongoing clinical trials network will hopefully provide more answers.
#LymeDiseaseAwarenessMonth

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More from @Lymenews

May 7, 2022
Dr. Scott Commings. Beyone Meat: What alpha-gal syndrome teaches us about the immune response to tick bites.
Dr. @scott_commins says they first began to notice patients complaining of delayed reactions to beef in mid-2000's.
Commings says Initially the only test they had for Alpha-gal was a two step skin test.
Read 13 tweets
May 7, 2022
Next is Dr. @aucott_john on Lyme disease and infection associated chronic illness. Lessons from COVID Long Haulers and ME/CFS.
Infection associated illness is not new. #LymeDiseaseAwarenessMonth
Dr @aucott_john quickly noticed the symptoms of #LongCOVID were very similar to #LongLyme. Can occur in patients with mild illnesss. Something similar in how these diseases are affecting humans (P.S. Long-haul does not occur post-flu.) #LymeDiseaseAwarenessMonth
Patients with chronic illnesses are often disbelieved. It is difficult as there are no diagnostic tests to prove "Long haul" is real.
Read 16 tweets
May 7, 2022
Jeff says they were able to present the @liv_lyme @TicktrackerAPP to the The National Association and County and City Health Officials (NACCHO) and the Centers for Disease Control and Prevention (CDC) during Vector Week. #LymeDiseaseAwarenessMonth
Since it's launch in 2018 @TicktrackerAPP has had over 8,000 submissions. Submissions peak in May-June. American dog tick was number one tick identified. #LymeDiseaseAwarenessMonth
Detail on @TicktrackerAPP submissions. They are working to improve the program to help better identify ticks especially nymphs. #LymeDiseaseAwarenessMonth
Read 5 tweets
May 7, 2022
Tickborne Disease Updates from Sue Visser, DrPH, MS Associate Directors for Policy and Extramural Program @CDCgov Division of Vector-borne Diseases Image
Visser pointing out that surveillance is comes from the states. ImageImage
Visser. Pointing out the challenges and opportunities for #LymeDisease surveillance. #LymeDiseaseAwarenessMonth ImageImage
Read 7 tweets
May 7, 2022
Dr. Jayakumar Rajadas on the striking similarities & possible therapeutic options for #LongCOVID & #LongLyme #LymeDiseaseAwarenessMonth
Dr. Rajadas, a pharmacologist by training, finding doxycycline is not clearing infection in the lab. However, mitomycin & azlocillin are working well. Prefers fewest number of molecules as treatment option (1 or 2 at most). #LymeDiseaseAwarenessMonth
Rajadas finding TLR2 interaction in both Borrelia and SARS-Cov-2 surface proteins, also elevation of quinolinic acid. #LymeDiseaseAwarenessMonth
Read 9 tweets
May 7, 2022
Next is Dr. Saravanan Thangamani @Thangamani_Lab Emergence of ticks and tick-borne diseases in NY.
Deer tick
Lone star tick
Dog tick
Asian longhorned tick
Dr. @Thangamani_Lab reviewing the many pathogens carried by Deer tick, Lone star tick, Dog tick, Gulf coast tick, and the invasive Asian longhorned tick. #LymeDiseaseAwarenessMonth
Dr. @Thangamani_Lab started a citizen science project in 2019 that allows citizens to send in ticks that they are able to use for research. number of ticks and the % pathogens they carry are increasing. #LymeDiseaseAwarenessMonth upstate.edu/whatsup/2021/0…
Read 5 tweets

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