Helmi Sulaiman Profile picture
ID physician at the University of Malaya.

Nov 2, 2022, 7 tweets

Myth: Bactericidal Agents Are Necessary for the Treatment of BSI at #idweek2022

A nice and easy-to-follow account of bactericidal vs. bacteriostatic agents and activity
@SyamhaninA @fikreeahmad @adammashraff @shaharudeen @andrewchangID @Rasidah @suraya_sudenia @cllau888

@SyamhaninA @fikreeahmad @adammashraff @shaharudeen @andrewchangID @Rasidah @suraya_sudenia @cllau888 Cidality is NOT an intrinsic property of an antibiotic
e.g., for the same drug (TMP-SMX), we have 2 different properties against 2 different organisms:
1) Static against Steno
2) Cidal against E. coli

And in a subgroup analysis of LNZ (a bacteriostatic agent), the data favors it over the bacteriocidal agents!

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