Polyminimyoclonus!!!
“intermittent, low-amplitude, arrhythmic movements of the hands, with amplitudes just sufficient to produce visible movements of the joints.”
American child neurologist Alfred J. Spiro (1930–2019)
#MedTwitter #neurotwitter #EndNeurophobia #tweetorials
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Features
- Mostly noticed when maintaining a posture (outstretched hands) or during action (initial phase of the movement)
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Pathophysiology @JackyGanguly
Motor cortex
- execution of fractionated muscle activation
Anterior horn cells
- generators of complex fasciculation
Possible role of brainstem, cerebellum, and basal ganglia
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How to clinically differentiate peripheral from central origin?
EEG & EMG
Peripheral: denervation
Central: parkinsonism or epilepsy
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Polyminimyoclonus: Hirayama disease
“low amplitude, intermittent, arrhythmic”
dx.doi.org/10.1136/bcr-20… via: BMJ Case Reports
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Polyminimyoclonus: Hirayama disease
“low amplitude, intermittent, arrhythmic”
dx.doi.org/10.1136/bcr-20… via: BMJ Case Reports
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Polyminimyoclonus: Spinal muscular atrophy type-3 (Kugelberg–Welander disease)
“low amplitude, intermittent, arrhythmic”
doi.org/10.1136%2Fbcr-… via: BMJ Case Reports
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Polyminimyoclonus: Spinal muscular atrophy
“low amplitude, intermittent, arrhythmic”
doi.org/10.1016/j.pedi… via: Pediatric neurology
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Polyminimyoclonus: Chronic Aluminium Toxicity
“low amplitude, intermittent, arrhythmic”
doi.org/10.5334%2Ftohm… via: Tremor Other Hyperkinet Mov (N Y)
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Polyminimyoclonus: Hirayama disease
“low amplitude, intermittent, arrhythmic”
doi.org/10.1007/s13760… via: Acta Neurol Belg
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Polyminimyoclonus: Progressive myoclonic ataxia
“low amplitude, intermittent, arrhythmic”
polymyoclonus and postural tremor
doi.org/10.1016/j.park… via: Parkinsonism Relat Disord
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Polyminimyoclonus
“low amplitude, intermittent, arrhythmic”
youtube.com/shorts/IXvFByD… via: Dr Sudhir Kumar
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Polyminimyoclonus
“low amplitude, intermittent, arrhythmic”
via: Dr. Vijaya Mishra
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Polyminimyoclonus: Myoclonus Renal Failure Syndrome
“low amplitude, intermittent, arrhythmic”
postural tremor, action myoclonus, and polyminimyoclonus
via: JAMA Network
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Polyminimyoclonus: Congenital myoclonus syndrome
“low amplitude, intermittent, arrhythmic”
youtube.com/shorts/Ps9zHOt… via: Daniel Jones
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Polyminimyoclonus: Renal failure syndrome
“low amplitude, intermittent, arrhythmic”
via: Daniel Jones
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Polyminimyoclonus: Hallermann-Streiff syndrome
“low amplitude, intermittent, arrhythmic”
via: Daniel Jones
17/
Polyminimyoclonus
“low amplitude, intermittent, arrhythmic”
via: Neurozone videos
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Polyminimyoclonus: Hirayama disease
“low amplitude, intermittent, arrhythmic”
via: Neurology Journal
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Polyminimyoclonus
“low amplitude, intermittent, arrhythmic”
youtube.com/shorts/geFfzqo… via: Ndd Workshop
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Polyminimyoclonus
“low amplitude, intermittent, arrhythmic”
postural tremor and polyminimyoclonus
youtube.com/shorts/d5f6tyI… via: Tech, Med & More
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Polyminimyoclonus: Morvan syndrome
“low amplitude, intermittent, arrhythmic”
via: The Lancet
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Polyminimyoclonus
“low amplitude, intermittent, arrhythmic”
youtube.com/shorts/kisJVUd… via: Dr.M. A Aleem
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Polyminimyoclonus: Myoclonus-dystonia syndrome
“low amplitude, intermittent, arrhythmic”
postural tremor, action myoclonus, polyminimyoclonus
youtube.com/shorts/qgcnI0_… via: Hannah Émile
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