James Noake Profile picture
Consultant in Musculoskeletal, Sport & Exercise Medicine. Interest in difficult stuff; hip, groin & gluteal pain; diagnostics; ultrasound. Pro rugby Dr 10 yrs +

Jun 9, 2023, 24 tweets

Stress fractures - a detailed thread 🦴🦴🦴

I thought I'd put together an overview & some clinical nuggets from the 'coal-face'

First up, I prefer to call them 'bone stress injuries' - majority don't have a # line on imaging & the language can be scary / nocebic for some

Pathophysiology & risk factors

Stress fractures-
Occur in normal bone that is placed under abnormal / persistent load & strain ('training / sporting error')

Insufficiency fractures-
Occur in bone that is under normal strain but is structurally vulnerable eg metabolic conditions

In reality, can be a combination of both to varying degrees - not 'black & white'

Special mention goes to RED-S which often underpins BSI in athletes - men & women!

Ask about relationship with food (past & present) & menstrial history - periods are a barometer of athlete health

At a granular level, bone physiology, its hormonal control & homeostasis is complex - but the fundamentals are pretty straight forward ⬇️

Grading

Fredericson classification originally created for Medial Tibial Stress Syndrome (MTSS) - now extrapolated to other BSIs

Is it helpful?🧐

I occasionally see high grade injuries with minimal pain - & low grade stress reactions with significant symptoms & functional loss

However, generally if cortical involvement with fracture line = significant injury & correlates with extended RTP / running timescales

A useful platform for discussion with patient around severity of injury and respecting the injury & realistic timescales

High vs Low risk BSI

Some stress #s need to be treated with extra respect & caution - see table

These are typically under sustained high strain coupled with relatively poor blood supply

These are more likely to go through delayed union & take longer to recover - or indeed even need early orthopaedic opinion - tension / lateral side neck of femur is a good eg

Keep them on your clinical radar & assess specifically for them - lower threshold for imaging

Presentation

Gradual onset with persistent impact activity - but occasionally patient describes acute onset pain/ 'crack'

Pain on impact / 'first step' - tendon conditions often ‘warm up’ - unusual with BSI

Some with lower grade BSI can often run through it, but ⬇️performance

Rest & night pain when high grade

Ache, throb at rest - sharp, shooting under load - pelvic & proximal femur BSIs can feel 'neural' & refer into lower limb

Description of loss of power output, control, heaviness

Assessment

Lower limb & pelvic - 'Hop test' invariably positive - shut down, reduced power output

Sacral stress # - SIJ provocation tests

FADIR test positive for pubic & neck of femur BSI

Swelling & oedema (esp foot & ankle) around bony tenderness site in absence of trauma

Imaging - X-ray

X-rays ➡️poor sensitivity eg ~ 85% of pelvic stress #s are missed on plain films

More likely to pick up a BSI in later stages (eg 4 weeks+) due to callus formation

But better than nothing, esp if suspecting high grade high risk BSI eg ant tibial

MRI

Close to 100% sensitivity & the modality of choice

It picks up medullary bone oedema (earlier stress reaction) which X-ray & CT can't

It's more sensitive than 2 phase bone scan - plus bone scan non-specific

It also assesses periosteal & wider soft tissue involvement

MRI VIBE sequences ('pseudo CT') are excellent for detailed assessment of pars stress injuries


This can be repeated to assess pars bony healing which takes longer than other BSIs (~3-6 months)
journals.assaf.org.za/index.php/sajs…

CT

Misconception re CT being accurate at identifying stress

Excellent at picking up & delineating high grade cortical disruption or long-standing changes eg callus formation / periosteal changes

But it's not a first line modality - MRI is gold standard

Lower threshold for using CT alongside MRI in high risk BSI

Useful where concern re:

Fracture configuration or cortical involvement underestimated on MRI

Healing status / delayed union

Ruing out differential diagnosis eg tumour, osteomyelitis

Ultrasound

A quick useful tool at the point of care, time efficient

Can pick up periosteal reaction, callus formation, local soft tissue swelling & inflammation

Like x-ray & CT, won't pick up medullary bone oedema

On balance probably more sensitive than x-ray

Management

Ideally an MDT approach best esp if RED-S part of the picture - see slide below

Communication key - ? SEM led

Pharmacological Rx 💊💊- specialist decision in difficult cases eg bisphosphonates, teriparatide, transdermal oestrogen (RED-S)

Nutritional & dietary modifications - eg improving macro / calorie intake in cases of low energy availability (LEA)

Vitamin D

Other adjuncts eg shockwave therapy, LIPUS - controversial

Rehab fundamentals

Return to running & load progressions guided by pain levels & function

Beware 'lag phenomenon' when assessing pain response / flare on⬆️load - delay over 2-3 days

Generally 12-16 weeks RTR

<8 weeks seems a recipe for recurrence & back to 'square 1'

Challenge 😤🙄 the small number of patients who have low levels of pain - or pain settles v quickly with early offload - but high grade stress radiologically

In these cases seems sensible to respect physiology & set arbitrary number of weeks before moving into RTR

Some clinicians might not agree with this & have a more pragmatic approach

@rwilly2003 paper has suggested that with MTSS, if pain free for 5 days can begin graded RTR

So clearly can't be rigidly prescriptive / recipe based - every patient different due to personal factors ++

Tips:

Time scales variable
Respect physiology
Not ‘one size fits all’
Step count?
Pragmatic approach to cross training
Parallel S&C programme
Education
Alter G – graded exposure?

Why aren't they getting better?

Compliance aside - misdiagnosis might be the cause -

eg rheumatological - enthesopathy with florid bone oedema

Osteoid osteoma tumour - eg proximal femur & calcaneum - here CT will help differentiate

Share this Scrolly Tale with your friends.

A Scrolly Tale is a new way to read Twitter threads with a more visually immersive experience.
Discover more beautiful Scrolly Tales like this.

Keep scrolling