Let’s take a minute to recap our latest blog post on a pretty daunting hematological emergency🩸
A thread 🧵 1/7 #MedEd #MedTwitter
An imbalance between ADAMTS-13 and von-willebrand factor can lead to catastrophic physiological damage 💔
🧵 2/7
The classic FATRN presentation actually only occurs in less than 7% of cases 😳
Instead, look for:
🧠 CNS symptoms - 60% of cases
🤮 GI symptoms - 35% of cases
🫀 Cardiac symptoms - 25% of cases
🧵 3/7
Send an ADAMTS-13 Activity but most labs won't have it resulted for a few days so here are other lab findings to search for in the ED 🧪
🧵 4/7
Since we can't rely on confirmatory testing in the ED, use the PLASMIC score to risk stratify patients and help guide management 🧠
🧵 5/7
Get your juniors ready to place a dialysis catheter since the most effective treatment for TTP will require one 💉
🧵 6/7
Head over to our website for references and a more comprehensive dive into TTP
Link: coreem.net/core/thromboti…
🧵 7/7
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