Thread by @DrJackKruse

While the tweet is correct, my tribe knows Dr. B is someone's advice to avoid. He has no idea about the quantum biology of NO. His advice was so bad I had to cancel a member's membership over this.

2. NO to excess is a danger. I saw this first hand in New Orleans during HIV.

3. UV sunlight stimulates vitamin B12 synthesis, red blood cell production, NO release (lowering blood pressure, increasing venous oxygen), and stem cell activity, with corrin-bound NO modulating its bioactivity as a GOE legacy against oxygen toxicity.

The Coulomb force (∇·E = ρ/ε₀) amplifies skin’s electrostatic fields, optimizing these processes, with potential significance in Nodes of Ranvier (nerve conduction) and retinal vasculature (blood flow).

In California for example, nnEMF, smog, and lifestyle factors disrupt this photobiology, reducing 25(OH)D, B12, and NO, driving many diseases like atopy, eczema and autism (1 in 24 children, 2025). Maternal disruptions in this system induce many epigenetic changes, amplifying transgenerational risks versus Florida. ICD-10 code use in California W90.0 supports nnEMF’s role in how excess NO can harm.

4. Corrins bind nitric oxide (NO), quenching its bioactivity, making sure it acts locally and globally. No enhances blood flow but it decreases ATP production and this legacy action is tied to the GOE to protect us from oxygen toxcity. The real action of NO is to increase the heat sink in cells. This has massive effects on the semiconduction inside of cells. There has to be a big story here for the Coulomb force and skin, brain, eyes. It might be a bigger deal in the Nodes of Ranvier and in retinal vascular system in diseases like ALS.

5. Sunlight’s Photobiological Effects on B12 & NO are antagonistic by design to make its effects focal.

Vitamin B12 Synthesis: UV sunlight (particularly UVB, ~290–320 nm) can stimulate the synthesis of vitamin B12 (cobalamin) in the skin and/or gut microbiome by enhancing the activity of photolyase-like enzymes or influencing bacterial cobalamin production.

While direct evidence is limited, I have asked @SabinehazanMD and @dralexisjazmyn to study it because centralized gastro MDs and PhDs of th emocrobiome won't because it breaks their paradigm of current religious belief.

First principles teach the Savage that UV exposure increases B12 levels in some species (e.g., algae), suggesting the first two domains of life use many photobiological pathways. This must involve quantum excitation of corrin ring electrons, explaining why the human gut is filled with aromatic amino acids and things like serotonin, though the mechanism in humans requires further study because the NIH does not want this truth out. If people got in the sun it would negate the need for the FDA and BigHarma. This is why it is not studied.

Red Blood Cell Synthesis: UV sunlight enhances erythropoiesis (red blood cell production) by stimulating bone marrow activity, via NO-mediated signaling in the renin angiotensin loop via vitamin D-induced upregulation of erythropoietin (EPO). Studies show UV exposure increases hematocrit in all animals studied, and this supports my thesis, but remarkably no PhD can get funding to study humans because the results would destroy the power base of BigHarma and the FDA.

6. NO as a Photoswitch: NO electrifies the gut barrier via splanchnic vasodilation, modulates ROS/RNS, and links to ATP/ROS balance, acting as a rapid, local signal per Shannon’s information theory.

Gut Dysbiosis and Endothelial Dysfunction: Lack of full-spectrum sunlight (UV, blue-green) reduces NO, causing gut barrier breakdown, dysbiosis, and systemic diseases (e.g., PAD, glaucoma, eczema, autism), spreading via mitochondrial colonies.

HIF-1 and PER2 Link: HIF-1, tied to PER2, regulates circadian clocks and SIRT3 under hypoxia, influenced by sunlight, with evolutionary roots in the KT event favoring mammals over dinosaurs.

Red Light Potential: Intense red light may mimic sunlight’s PER system effects, offering a therapeutic avenue.

Coulomb Force and Electrification: Electrostatic fields (∇·E = ρ/ε₀) amplify photobiological signals in skin, gut, and neural tissues.

Orange County Context: nnEMF and malillumination exacerbate these disruptions, driving transgenerational risks in offspring in California.

Actionable Insights: Strategies to restore photobiology I teach ad nauseum on my Patreon blogs. patreon.com/DrJackKruse

7. What PhD Bryan is clueless on and you can see it Dr. Attia's reasoning too? This is why peripheral arterial disease is always/often associated with light induced diseases via the abscopal effect. The link is the aberrant use of the electromagentic spectrum to communicate to create NO to act as the photoswitch between electric and the magnetochemistry of free radicals and this creates the UPE spectra that control biochemistry actions.

RNS, include nitric oxide (NO), peroxynitrite, and nitroxylanion, is also an important class of oxidative bio-signal molecules. The corrins and B12 quench all this assuming you are doing life right.

Nitric oxide synthases (NOS) are a group of enzymes that produce NO from L-arginine (L-Arg), O2 and NADPH. Skeletal muscle contains three NOS subtypes, which are neuronal NOS (nNOS), inducible NOS (iNOS) and endothelial NOS (eNOS)

8. Modern lighting and the AC power grid affect all RNS and ROS production but really destroy NO production. RF/microwave cell radiation impairs production of NO from arginine by eNOS. This, in turn, induces oxygen variations in the cytosol and matrix by altering blood pressure and partial pressures of oxygen in a cell to induce endothelial dysfunction in the target organ.

Mitochondria are intimately involved in importing nitrogen into tissues to create the substrates that eventually become NO when sunlight is present. This is why Bryan is talking up foods with nitrates and nitrites. People who live in shit holes are super sensitive to them because they live in shit light. Bryan does not have this sophistication understanding. You must. Nitrogen substrates are not created from the direct synthesis by eNOS.

Nature provided the clue to me why humans got rid of Vitamin C for glutathione in this AMO physics dance. When Vitamin C is missing in subcutaneous tissues, glutathione become more reactive with locally produced NO. This mimics a radical pair or triad effect we see in the magnetic avian compass navigation. Here was more evidence for me that magnetochemistry in humans being used and timing was more important than I'd ever imagined.

9. When glutathione and nitric oxide are powered by terrestrial sunlight this allowed humans to produce S-nitrosoglutathione (GSNO). I think this is why human primates lost the majority of their integumentary hair to absorb more solar light to power their new territory in the frontal regions and it added a ton of charge density to the gut. This is why is shortened and got smaller. The better the skin absorbed solar photons the more melanin from the hair follicle migrated to the interior and the more NO was made in the skin and gut.

This allowed the skin & gut to become a MASSIVE charge capacitor for the brain and heart by allowing the skin to become a depot station to store massive amounts of nitric oxide. This is why human immune T cells are so common in the skin and why leptin was placed in SQ fat. Other primates do not have these phenotypes even thought their genomes are close to identical.

This told me the primate body plan was changed using magnetochemistry and not genetic therapy all indiced by the timing of photoswitching in the skin. Solar light completely induced this evolutionary change in our primate cousins. Everything I believed was thrown out the window from medicial school that day 20 yrs ago. We never need genes to change this.

10. We used timing to change the metabolic pathways in the skin using hair loss and removal of Vitamin C from the radical triad mechanism to do it. As a consequence of this dance using more light on the skin, keratinocytes were able to sense more visible light combinations with purple, blue, and green light to easily photocatalyze the release of NO from glutathione. Not only does this cause a relaxation of the blood vessels, but it also frees up glutathione to react with hydrogen sulfide gas to produce sulfate to make every other chemical in the skin water soluable to get access to body parts to have global effects. This is how light develops its abscopal effects in your tissues and each tissue zip code matters. The optical density is designed to change and free radicals are what is behind our biological kaleidoscope.

11. No one has figured out how this all works in humans but this is how I have seen it for 20 plus years and I got a big head start.

To date no one has published a thing using my ideas. But I can explain why subtraction of Vitamin C in humans links to hair loss.

It also explains why balding people all have bad surface topology. None of the photoswitches work. This explains most of the integumentary and ocular diseases we see today. It also explains obesity, too. It also explains autoimmunity.

As a throw in for my neurosurgery life it finally explained to me why humans get aneuysms and AVMs and the gut barrier goes boom when it happens.