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Maru Profile picture
@mellases
Apr 12, 2019 • 3 tweets • 1 min read • Read on X
Tengo 12 seguidores ! #myfirstTweet Gracias a todes, no los voy a defraudar. #OSI
oh no, use mal el lenguaje inclusivo. 34 segundos y ya los defraudé.
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More from @mellases

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Sep 7, 2020
Hello @LatinXChem! Today I want to share my latest work about the mechanisms of assembly of CuA Site by mitochondrial metallochaperones. Done at @IBR_CONICET and @VilaLab, in collaboration with @soy_MAC and @labriataphd. #LatinXChem #LatinXChemBio #BIO045 (1/5) Image
We found that A. thaliana Sco1 binds both Cu(I) and Cu(II) with high affinity. We analyzed both copper sites by spectroscopic methods, XRay crystallograpy and DFT, confirming that Cu(I) tri-coordinated (2SCys-NeHis) and Cu(II) tetra-coordinated (2SCys-NeHis-H2O) (2/5) Image
To test the activity of AtSco1, we first designed a soluble model of AtCoxII. We confirmed the formation of CuA site and the possibility of monitoring all four possible oxidation and metallation states of the protein by NMR. (3/5) Image
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