f1/ Trump keeps pushing people to (Hydroxy)Chloroquine.
I’ve been collecting & annotating credible information from @UCSF experts on COVID-19, as it appears, in the subthreads of
CV1-
This thread selects those relevant specifically to HCQ & CQ.
I’ve been collecting & annotating credible information from @UCSF experts on COVID-19, as it appears, in the subthreads of
CV1-
This thread selects those relevant specifically to HCQ & CQ.
f2/ 03/19/20 @annieluet discussed potential treatments of COVID-19, in internal meeting primarily geared for doctors. I’ve annotated to help general public.
Take a quick look at the tweets, then watch video of her presentation.
a5-a10.2, a13
Take a quick look at the tweets, then watch video of her presentation.
a5-a10.2, a13
f3/ 03/24/20 This is part of a 28-minute interview @Bob_Wachter did with @annieluet, very useful as she had time to explain more, easily accessible to general audience. I learned from whole thing:
b1-12
but see especially b5-b6 on CQ/HCQ : NEED TRIALS.
b1-12
but see especially b5-b6 on CQ/HCQ : NEED TRIALS.
f4/ 03/26/20 Presentation from @annieluet about randomized clinical trials (RCTs) at @UCSF.
c8-c10 discusses big trial started with another drug, Remdesivir, but structured to allow addition of others like HCQ. She notes controversy around HCQ
c8-10
c8-c10 discusses big trial started with another drug, Remdesivir, but structured to allow addition of others like HCQ. She notes controversy around HCQ
c8-10
f5/ 03/02/20 @UCSF researchers/clinicians did COVID-19 presentations & panel sessions (2 hours)
@annieluet's comments on HCQ are:
e6-7
She reviews a few papers in the news, ending with "Concerns about safety with unmonitored use & drug supply".
@annieluet's comments on HCQ are:
e6-7
She reviews a few papers in the news, ending with "Concerns about safety with unmonitored use & drug supply".
f6/ 04/04/20 That’s all for now, but this thread will be updated with more extracts as they happen. See also comments from others about various studies in this thread:
A-T
A-T
f7/ 04/16/20 Careful, well-informed, high-quality info:
@UCSF Infectious Disease expert @annieluet gave great update on treatments & trials (she runs real ones), as more studies kept being reported, although still not good RCTs.
Watch, incl Q&A at end.
youtube.com/watch?v=o1I2Kl…
@UCSF Infectious Disease expert @annieluet gave great update on treatments & trials (she runs real ones), as more studies kept being reported, although still not good RCTs.
Watch, incl Q&A at end.
youtube.com/watch?v=o1I2Kl…
f8/ @annieluet, more on HCQ & CQ:
“No signal yet for clinical or viral efficacy
Concern for cardiac toxicity, especially with other QTc prolonging agents.”
(Dosage issue remains unclear: is there a dosage that has useful effect for COVID that is not also toxic for some people?)
“No signal yet for clinical or viral efficacy
Concern for cardiac toxicity, especially with other QTc prolonging agents.”
(Dosage issue remains unclear: is there a dosage that has useful effect for COVID that is not also toxic for some people?)
f9/ @annieluet summarizes potential treatments.
Safety varies, No RCT data demonstrating efficacy yet.
She’s on 5 of 8 @UCSF Clinical trials.
1:04:00 @Bob_Wachter asks her advice for frontline clinicians.
UNLIKE TV-personality "doctors", real experts explain uncertainties.
Safety varies, No RCT data demonstrating efficacy yet.
She’s on 5 of 8 @UCSF Clinical trials.
1:04:00 @Bob_Wachter asks her advice for frontline clinicians.
UNLIKE TV-personality "doctors", real experts explain uncertainties.
f10/ There is now a Wikipedia page for Professor Luetkemeyer:
en.wikipedia.org/wiki/Annie_Lue…
en.wikipedia.org/wiki/Annie_Lue…
