Thread by @DrSimonAshworth

How should we consider #COVID19?

This is primarily a vitally induced thrombotic disease spread by droplets

Post-mortems tell us the virus causes endothelial damage and overt blood clots in both small and large vessels #COVID19

The clinical features fit with this as the primary pathology

Pulmonary arterial thrombosis causes breathlessness and high alveolar dead space #COVID19

I am going to postulate that pulmonary venous thrombosis causes the airway swelling that has been reported #COVID19

The lungs are worst involved mainly because they get 100% of our blood flow, but kidney, gut and brain involvement are all recognised… #COVID19

#COVID19 is not all about ventilators it’s all about thrombosis…

So what are the treatment implications?

I would love to know if other doctors have seen patients with severe hypoxia from COVID who are on Clopidogrel? I haven’t…

What about aspirin, rivaroxoban, apixaban, warfarin, etc?

#COVID19

Virally (fat fingers)

I meant bronchial venous 🙄