Share this page!

Enter URL or ID to Unroll

You can paste full URL like: https://x.com/threadreaderapp/status/1644127596119195649
or just the ID like: 1644127596119195649

How to get URL link on X (Twitter) App

  1. On the Twitter thread, click on or icon on the bottom
  2. Click again on or Share Via icon
  3. Click on Copy Link to Tweet
  4. Paste it above and click "Unroll Thread"!
  5. More info at Twitter Help
Dr. Deanna Santer Profile picture
@drdeannasanter
Apr 14, 2020 • 3 tweets • 2 min read • Read on X
Honored to be a part of this amazing #IFNLambda expert group brought together by @prokuninaolsson to bring awareness to using IFN-lambda 1 in #COVID19 patients! Through zoom and online editing we were able to quickly put this together for @JExpMed doi.org/10.1084/jem.20…
We discuss the major benefit IFNL1 may provide vs type I IFNs in #COVID19 or future emerging viruses with potentially less side effects/inflammation, but also discuss potential risks when we need more data specifically in humans which is a focus of my projects in the lab.
We are happy to see #Eiger will support IFNL1 clinical trials starting in the near future when patients desperately need new treatments but we recommend starting in patients with less serious disease or healthcare workers

• • •

Missing some Tweet in this thread? You can try to force a refresh
　

Keep Current with Dr. Deanna Santer

Dr. Deanna Santer Profile picture

Stay in touch and get notified when new unrolls are available from this author!

Read all threads

This Thread may be Removed Anytime!

PDF

Twitter may remove this content at anytime! Save it as PDF for later use!

Try unrolling a thread yourself!

how to unroll video
  1. Follow @ThreadReaderApp to mention us!

  2. From a Twitter thread mention us with a keyword "unroll"
@threadreaderapp unroll

Practice here first or read more on our help page!

More from @drdeannasanter

Dr. Deanna Santer Profile picture
Aug 30, 2020
I'm excited to make it #TwitterOfficial that I will be joining the Dept of Immunology at the University of Manitoba as an Assistant Professor and GSK Research Chair in Immunology of Infectious Diseases as of Nov 1, 2020!! @UM_Immu @UM_RadyFHS @umanitoba #newPI 1/5
I am so grateful to have this opportunity especially in these tough times. Thanks to all my mentors & colleagues over the yrs (most are not on Twitter). 2 undergrad summers with @NRC_CNRC & an amazing 5yrs at @UW Immunology with mentor Dr. Keith Elkon before back to 🇨🇦 2/5
Thank you to Dr. Michael Houghton & Dr. Lorne Tyrrell @LKSIoV for your mentorship & allowing me to build my own research program that I am excited to bring to @umanitoba where many new collaborations are possible. Thanks to everyone @UAlberta_MMI who helped along the way! 3/5
Read 5 tweets
Dr. Deanna Santer Profile picture
Aug 28, 2020
Thank you Dr. Marco Cassatella for highlighting our @PLOSPathogens article in @Facultyopinions ! The recommendation nicely sums up our findings about IFNLR exp on specific human immune cells & soluble IFNLR1 (only in primates) inhibiting responses doi.org/10.1371/journa… 1/4
Cassatella M: Faculty Opinions Recommendation of [Santer DM et al., PLoS Pathog 2020 16(4):e1008515]. In Faculty Opinions, 27 Aug 2020; 10.3410/f.737851343.793577620 2/4
The lack of responsiveness to IFNLs and lack of IFNLR1 expression on human neutrophils was also shown by @rishirajgoel et al. doi:10.1073/pnas.1916897117 by scRNA seq and other scRNA seq datasets show low to no IFNLR1 mRNA in human neutrophils... 3/4
Read 4 tweets
Dr. Deanna Santer Profile picture
Jun 25, 2020
Super excited and thankful to @CIHR_IRSC 🍁 for supporting our project to characterize IFN-lambda1 as a treatment for #COVID19 - our amazing team includes Lorne Tyrrell and myself @UAlberta_FoMD, and @JJFeld and Adam Gehring @UHN The clinical trial has already started... 1/3
To be ranked #1/339 was an extra bonus after working late nights to put this together in under 2 weeks! I know we will learn a lot about #COVID19, but also how IFN-lambda 1 modulates our immune system which has implications for potentially using IFNL1 against other viruses! 2/3
If you or someone you know in the Toronto area was recently diagnosed to be #SARSCoV2 positive, then @JJFeld is still enrolling patients for the trial 3/3 😀
Read 4 tweets

Did Thread Reader help you today?

Support us! We are indie developers!

This site is made by just two indie developers on a laptop doing marketing, support and development! Read more about the story.

Become a Premium Member ($3/month or $30/year) and get exclusive features!

Become Premium

Don't want to be a Premium member but still want to support us?

Make a small donation by buying us coffee ($5) or help with server cost ($10)

Donate via Paypal

Or Donate anonymously using crypto!

Ethereum

0xfe58350B80634f60Fa6Dc149a72b4DFbc17D341E copy

Bitcoin

3ATGMxNzCUFzxpMCHL5sWSt4DVtS8UqXpi copy

Thank you for your support!

Follow Us!

Send Email!

:(