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39yo male, BMI=31, no other risk factors. Fever and myalgia started 6 days ago. #COVID19 (+). Tx with steroids & tocilizumab during hospital stay. Day 19➡️Galactomannan antigen positive (Aspergillus). #CT on day 6 with classic #COVID19 pattern. 1/4
...#CT on day 30 shows 3 rounded lesions with a thick wall in the upper lobes not present on initial CT, suggestive of invasive Aspergillosis. Only risk factors are immunosuppressant drugs used during hospital stay. Next step ➡️ Biopsy?? ... 2/4
... Here are the #CXR at day 2,6,10 and 14 after the onset of symptoms. Notice how CXR is normal on day 2 and significantly worse on day 10 (peak stage of symptoms). 3/4
... Now #CXR on day 17, 21, 26 and 30. Pt was intubated on day 17. Is #COVID19 + Aspergillus just a coincidence?. This paper suggests otherwise ➡️ papers.ssrn.com/sol3/papers.cf… 4/4
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