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US Nursing home deaths from COVID-19 top 10,000

abcnews.go.com/Health/coronav…
Nursing homes in Fresno, CA:

abc30.com/nursing-home-c…
@JAMA_current op-ed by @ml_barnett & @DavidCGrabowski

jamanetwork.com/channels/healt…
Challenges and Priorities in Responding to COVID-19 in Inpatient Psychiatry

ps.psychiatryonline.org/doi/10.1176/ap…
Coronavirus on the Inpatient Unit: A New Challenge for Psychiatry by @shrinkrapdinah

medscape.com/viewarticle/92…
also by @shrinkrapdinah at @MDEdgePsych

mdedge.com/psychiatry/art…
Guidance for nursing homes by @CDCgov

cdc.gov/coronavirus/20…
Oops, wrong link on nursing homes in the UK above:

theguardian.com/society/2020/a…
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Coverage at @NewYorker by @mashagessen

newyorker.com/news/news-desk…
Rockland Psychiatric Center and Pilgrim Psychiatric Center in NY

nytimes.com/2020/04/24/nyr…
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More from @psychunseen see all

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Joe Pierre, MD
@psychunseen
1/13

I did a bit of reading on #coronavirus research today, loosening the cobwebs of what I remember from majoring in molecular biology at MIT.

Per @K_G_Andersen's paper below, the structure of SARS-CoV-2 makes it a highly improbable man-made virus.

nature.com/articles/s4159…
2/13

The short summary is that the spike protein that it uses to enter human cells is similar to that of #SARS_COV_2 (the original one that resulted in the 2002-2003 SARS epidemic), but has differences that actually seem to make it LESS of a good fit.
3/13

So basically, it doesn't make sense that scientists hoping to make a bioweapon would fabricate something inferior to what already exists.
Read 14 tweets
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Joe Pierre, MD
@psychunseen
Re-reading The Plague by Albert Camus and thought I'd start a pithy quotation thread.

The Plague is a 1948 work of fiction that is said to be allegorical, but some of the passages are just so similar to what we're going through now.

Which is really the beauty of literature.
1) Everybody knows that pestilences have a way of recurring in the world; yet somehow we find it hard to believe in ones that crash down on our heads from a blue sky. There have been as many plagues as wars in history; yet always plagues and wars take people equally by surprise.
2) When a war breaks out, people say: “It’s too stupid; it can’t last long.” But though a war may well be “too stupid,” that doesn’t prevent its lasting. Stupidity has a knack of getting its way; as we should see if we were not always so much wrapped up in ourselves.
Read 45 tweets
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Joe Pierre, MD
@psychunseen
Is #azithromycin (an antibiotic, not an antiviral) + #chloroquine (an antimalarial) effective?

Maybe, maybe not. This is why clinical trials are vital... even when the outcomes are negative.

nytimes.com/2020/03/18/hea…
meanwhile, when we have political leaders who don't understand science and the necessity of randomized clinical trials to demonstrate safety/efficacy...

nytimes.com/2020/03/20/hea…
here's the link to the clinical trial on hydroxychloroquine + azithromycin... NOT randomized, NOT blinded, only N=6 pts treated with combination treatment = take the results with a HUGE grain of salt

mediterranee-infection.com/hydroxychloroq…
Read 6 tweets

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