Thread by @StephenVLiu

#ASCO20 Excellent presentation by @HornLeora on the #TERAVOLT initiative - a global registry describing patients with thoracic malignancy and COVID19. #OncoAlert #LCSM

#TERAVOLT is such an impressive effort, spearheaded by @marinagarassino. Flurries of emails sent on March 15, 2020 and a protocol approved 5d later with 200 patients presented at #AACR20 and 400 patients at #ASCO20! Driven by passion and a deep collaborative spirit. #OncoAlert

#ASCO20 An interesting observation in #TERAVOLT was the association of steroid use and anticoagulation (at #COVID19 diagnosis, not as an intervention) with higher mortality in patients with lung cancer. Months ago, we would not have predicted this. #OncoAlert #LCSM

#ASCO20 In #TERAVOLT, the mortality of patients with lung cancer and #COVID19 was 35.5%. The hospitalization rate was 78.3%. Some of these numbers are influenced by the time/region most heavily represented in the sample set but striking numbers by any measure. #LCSM

#ASCO20 Multivariate analysis in #TERAVOLT identifies older age, PS 1, prior steroids and use of chemotherapy were associated with higher risk of death with #COVID19. Gender, BMI, smoking status and stage did not influence risk. Such impressive work with more analyses underway!

#ASCO20 To sites not already involved in #TERAVOLT, visit the site below for more information. Our regulatory approval @LombardiCancer was quick and the data entry is user-friendly and secure. Amazing work by @marinagarassino @HornLeora #OncoAlert

teravolt-consortium.org