Dana M. Lewis | #OpenAPS 🤖 Profile picture
Jun 1, 2020 4 tweets 2 min read Read on X
It's so hard to lose a friend. 💜
I miss @mjseres. It makes my throat ache and my eyes run, three days in a row, to think about the world without him.

On a scale of 1 to kindest human you've ever met...he was the kindest human you've ever met.
When people ask for non-diabetes examples of #WeAreNotWaiting, @mjseres was the first person I talked about, and it was always an honor to help share his story. He saw a problem, designed a solution, and was building the future where more people could access better care and QOL.
I am glad he had such a ripple effect, because I know his work will continue & keep making the world a better place. But I also miss him deeply & miss what else he might have been able to help us all achieve.

Big hugs to @mjseres family and all of his loved ones and friends. 💜

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More from @danamlewis

Jun 22
1/ What if there was a tool to help identify who might have exocrine pancreatic insufficiency (EPI/PEI)?

EPI is a significant issue for many people with diabetes (likely more common than gastroparesis or celiac).

Here's how such a tool can help PWD👇🏼🧵

#ADASciSessions #ADA2024
2/ The Exocrine Pancreatic Insufficiency Symptom Score (EPI/PEI-SS) has 15 symptoms, rated by how frequent they are and how bothersome they are (aka severity).

n=324 ppl participated in a real-world survey.

n=118 were people with diabetes (PWD)!

#ADASciSessions #ADA2024
3/ Methods:

EPI/PEI-SS scores were analyzed and compared between PWD (n=118), with EPI (T1D: n=14; T2D: n=20) or without EPI (T1D: n=78; T2D: n=6), and people without diabetes (n=206) with and without EPI.

#ADASciSessions #ADA2024
Read 10 tweets
Jun 6, 2022
📣 Presentation of the primary outcome results from the CREATE Trial, which assessed open source automated insulin delivery (AID) compared to sensor-augmented pump therapy (SAPT) in adults & kids with T1D, at #ADA2022!

@DrMartindeBock1 presenting on behalf of CREATE team.

1/
Shout out to the amazing CREATE study team.

(PS - there’s another publication from our team about HCPs learning experience on open source AID for this study, too! doi.org/10.1111/dme.14…)

2/ #ADA2022
The CREATE trial aimed to study the efficacy and safety of an open source automated insulin delivery system, with a large scale, long term randomized controlled trial.

3/ #ADA2022
Read 15 tweets
Jun 5, 2022
I just realized it's been 3 (!) years since I published my book on automated insulin delivery, with the goal of helping increased conversation and understanding of AID technology for people with diabetes, their loved ones, and healthcare providers!

I'm still very proud that it is available to read for free online, free to download a PDF (both of which have been done thousands of times each: ArtificialPancreasBook.com), or as an e-book, paperback, and now hardback copy. Proceeds from the purchased copies go to Life For A Child.
And, more recently, it has also been translated into French by the wonderful Dr. Mihaela Muresan and Olivier Legendre!

The French translation is available in Kindle, paperback, hardback, or free PDF download formats as well.

Read 6 tweets
Sep 24, 2020
1/THREAD - my presentation is kicking off at #EASD2020 about open source automated insulin delivery.

(You can see a full version of my presentation here: bit.ly/DanaMLewisEASD…, or read the summary below!)
Note we should differentiate between open source (where the source of something is open), and DIY (do-it-yourself) implementations of open source code. Open source means it can be reviewed and used by individuals (thus, DIY or #DIYAPS) or by companies.

/2 #EASD2020
Open source automated insulin delivery (AID) has evolved since the first open source system, #OpenAPS, was made available in Feb 2015!

There are now three open source AID systems (OpenAPS, Loop, AndroidAPS) commonly used by the #DIYAPS community.

/3 #EASD2020
Read 25 tweets
Jun 13, 2020
THREAD:

Poster 988-P at #ADA2020 by Jennifer Zabinsky, Haley Howell, Alireza Ghezavati, @DanaMLewis Andrew Nguyen, and Jenise Wong: “Do-It-Yourself Artificial Pancreas Systems Reduce Hyperglycemia Without Increasing Hypoglycemia”

(PDF available at bit.ly/DanaMLewisADA2…)
This was a retrospective double cohort study that evaluated data from the @OpenAPS Data Commons (data ranged from 2017-2019) and compared it to conventional sensor-augmented pump (SAP) therapy from the @Tidepool_org Big Data Donation Project. #ADA2020
One month of CGM data (with more than 70% of the month spent using CGM), as long as they were >1 year of living with T1D, was used from the @OpenAPS Data Commons. People could be using any type of DIYAPS (OpenAPS, Loop, or AndroidAPS) and there were no age restrictions. #ADA2020
Read 12 tweets
Jun 13, 2020
THREAD:

Poster 99-LB at #ADA2020 by @danamlewis, @azure_dominique, and Lance Kriegsfeld, “Multi-Timescale Interactions of Glucose and Insulin in Type 1 Diabetes Reveal Benefits of Hybrid Closed Loop Systems“

(full content also available at bit.ly/DanaMLewisADA2…) Image
Background - Blood glucose and insulin exhibit coupled biological rhythms at multiple timescales, including hours (ultradian, UR) and the day (circadian, CR) in individuals without diabetes. But, biological rhythms in longitudinal data have not been mapped in T1D. #ADA2020
It is not known exactly how glucose and insulin rhythms compare between T1D and non-T1D, and whether rhythms are affected by type of therapy (Sensor Augmented Pump (SAP) or Hybrid Closed Loop (HCL)). #ADA2020
Read 26 tweets

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